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Search Results for " ( )-shikonin "

1

Compounds

6

Natural Products

Cat No. Product Name Synonyms Targets
T74814 PKM2/PDK1-IN-1
PKM2/PDK1-IN-1, one of shikonin thioether derivatives, is a dual inhibitor of PKM2 / PDK1 . PKM2/PDK1-IN-1 inhibits the proliferation of NSCLC cells, and induces apoptosis . PKM2/PDK1-IN-1 induces intercellular ROS produ...
Cat No. Product Name Synonyms Targets
T2897 (Rac)-Shikonin (±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid Others
(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...
T1125 Shikonin NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid TNF , NF-κB , Chloride channel , HIV Protease , PKM
Shikonin (Anchusa acid) is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-κB pathway and inhibit TNF-α. Shikonin decreases exo...
TN2439 (2-Methylbutyryl)shikonin Others
(2-Methylbutyryl)shikonin is a natural product from Lithospermum erythrorhizon Sieb. et Zucc.
T4958 (-)-Alkannin Alkannin,Shikonin Apoptosis , PI3K
(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a...
T1121 Podofilox Podophyllotoxin,(+)-Shikonin Microtubule Associated , Topoisomerase
Podofilox ((+)-Shikonin) is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irrit...
T5S2343 Acetylshikonin Acetyl shikonin Others , P450 , AChE
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...
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