Cat.No. |
Product Name |
Information |
Area |
T4301 |
AD80 |
AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTO... |
others |
T3579 |
PLX8394 |
PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF)... |
cancer |
T4167 |
B-Raf inhibitor 1 dihydrochloride |
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor. |
Others |
T4133 |
CCT196969 |
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It a... |
others |
T4194 |
CID-25014542 |
CID-25014542 is novel inhibitor of Raf kinases. |
Others |
T3711 |
RAF709 |
RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-R... |
|
T6971 |
RO5126766 |
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM,19 nM, 56 nM, a... |
Others |
T6895 |
MLN2480 |
MLN2480 is an oral, selective pan-Raf kinase inhibitor in clinical trials. |
Others |
T6882 |
LY3009120 |
LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for ... |
Others |
T6487 |
Encorafenib |
LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potentia... |
Cancer |
T6525 |
GW5074 |
GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on t... |
Cancer |
T2624 |
OSI 930 |
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth fact... |
Cancer |
T2473 |
PLX4720 |
PLX4720 is a specific and effective inhibitor of B-RafV600E (IC50=13 nM). |
Other |
T2382 |
Vemurafenibhot |
Vemurafenib (PLX4032, RG7204) is a novel and potent B-RafV600E inhibitor (IC50 of 31 ... |
Cancer |
T2295 |
SB590885 |
SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The sel... |
Other |
T2293 |
SGX-523 |
SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p... |
Cancer |
T2267 |
BQU57 |
BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft... |
Other |
T2074 |
B-Raf inhibitor 1 |
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor. |
Other |
T2070 |
CEP-32496 |
CEP-32496 is a highly potent inhibitor of BRAF. |
Other |
T1953 |
L-779450 |
L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays... |
Other |
T1903 |
Dabrafenibhot |
Dabrafenib is a selective inhibitor of mutated forms of BRAF kinase and is used alone... |
Cancer |
T1892 |
Kobe2602 |
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities... |
Other |
T1886 |
TAK632 |
TAK-632 is a potent pan-Raf inhibitor. |
Other |
T1876 |
Kobe0065 |
Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interact... |
Other |
T1851 |
ZM 336372 |
ZM 336372 is a potent and selective c-Raf inhibitor. |
Other |
T1845 |
B-Raf IN 1 |
B-Raf IN 1 is a B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM) inhibitor. |
Other |
T1792 |
Regorafenib |
Regorafenib is a Kinase Inhibitor. The mechanism of action of regorafenib is as a Pro... |
Cancer |
T0093L |
Sorafenib |
Sorafenib is a synthetic compound targeting growth signaling and angiogenesis. Sorafe... |
Cancer |
T0093 |
Sorafenib tosylate |
Sorafenib Tosylate is the tosylate salt of sorafenib, a synthetic compound targeting ... |
Cancer |
T6320 |
GDC-0879 |
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with a... |
Cancer |