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Raf

Cat.No.	Product Name	Information	Area
T4301	AD80	AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTO...	others
T3579	PLX8394	PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF)...	cancer
T4167	B-Raf inhibitor 1 dihydrochloride	B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor.	Others
T4133	CCT196969	CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It a...	others
T4194	CID-25014542	CID-25014542 is novel inhibitor of Raf kinases.	Others
T3711	RAF709	RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-R...
T6971	RO5126766	RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM,19 nM, 56 nM, a...	Others
T6895	MLN2480	MLN2480 is an oral, selective pan-Raf kinase inhibitor in clinical trials.	Others
T6882	LY3009120	LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for ...	Others
T6487	Encorafenib	LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potentia...	Cancer
T6525	GW5074	GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on t...	Cancer
T2624	OSI 930	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth fact...	Cancer
T2473	PLX4720	PLX4720 is a specific and effective inhibitor of B-RafV600E (IC50=13 nM).	Other
T2382	Vemurafenibhot	Vemurafenib (PLX4032, RG7204) is a novel and potent B-RafV600E inhibitor (IC50 of 31 ...	Cancer
T2295	SB590885	SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The sel...	Other
T2293	SGX-523	SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p...	Cancer
T2267	BQU57	BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft...	Other
T2074	B-Raf inhibitor 1	B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor.	Other
T2070	CEP-32496	CEP-32496 is a highly potent inhibitor of BRAF.	Other
T1953	L-779450	L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays...	Other
T1903	Dabrafenibhot	Dabrafenib is a selective inhibitor of mutated forms of BRAF kinase and is used alone...	Cancer
T1892	Kobe2602	Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities...	Other
T1886	TAK632	TAK-632 is a potent pan-Raf inhibitor.	Other
T1876	Kobe0065	Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interact...	Other
T1851	ZM 336372	ZM 336372 is a potent and selective c-Raf inhibitor.	Other
T1845	B-Raf IN 1	B-Raf IN 1 is a B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM) inhibitor.	Other
T1792	Regorafenib	Regorafenib is a Kinase Inhibitor. The mechanism of action of regorafenib is as a Pro...	Cancer
T0093L	Sorafenib	Sorafenib is a synthetic compound targeting growth signaling and angiogenesis. Sorafe...	Cancer
T0093	Sorafenib tosylate	Sorafenib Tosylate is the tosylate salt of sorafenib, a synthetic compound targeting ...	Cancer
T6320	GDC-0879	GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with a...	Cancer

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