Cat.No. |
Product Name |
Information |
Area |
T3196 |
GNF-7 |
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respec... |
Cancer |
T3071 |
GZD 824 |
GZD824 is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and... |
Cancer |
T3068 |
AT9283 |
AT9283 is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1... |
Cancer |
T3063 |
PD-173955 |
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Sr... |
Cancer |
T2640 |
DCC-2036 |
DCC-2036 (Rebastinib) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50... |
Cardiovascular System |
T2509 |
Tozasertib |
VX-680 (Tozasertib, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A (Kiap... |
Cancer |
T2429 |
GZD824 Dimesylate |
GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) an... |
Cancer |
T2328 |
Radotinib |
Radotinib, and sometimes referred to by its investigational name IY5511, is a drug fo... |
Cancer |
T2293 |
SGX-523 |
SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p... |
Cancer |
T2116 |
AEE788 |
AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multifo... |
Cancer |
T1817 |
GNF-2 |
GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl. |
Other |
T1803 |
GNF-5 |
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild... |
Other |
T1621 |
Imatinib Mesylate |
Imatinib mesylate is a specific tyrosine kinase receptor inhibitor with antineoplasti... |
Cancer |
T1524 |
Nilotinib |
Nilotinib is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinas... |
|
T1448L |
Dasatinib monohydrate |
Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family ... |
Cancer |
T0152 |
Bosutinib |
Bosutinib is a synthetic quinolone derivative and dual kinase inhibitor that targets ... |
Cancer |
T6311 |
Bafetinib |
Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5... |
Cancer |
T6300 |
Degrasyn |
Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UC... |
Cancer |