Bcr-Abl - Targetmol

Bcr-Abl

Cat.No.	Product Name	Information	Area
T3196	GNF-7	GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respec...	Cancer
T3071	GZD 824	GZD824 is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and...	Cancer
T3068	AT9283	AT9283 is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1...	Cancer
T3063	PD-173955	PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Sr...	Cancer
T2640	DCC-2036	DCC-2036 (Rebastinib) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50...	Cardiovascular System
T2509	Tozasertib	VX-680 (Tozasertib, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A (Kiap...	Cancer
T2429	GZD824 Dimesylate	GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) an...	Cancer
T2328	Radotinib	Radotinib, and sometimes referred to by its investigational name IY5511, is a drug fo...	Cancer
T2293	SGX-523	SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p...	Cancer
T2116	AEE788	AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multifo...	Cancer
T1817	GNF-2	GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.	Other
T1803	GNF-5	GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild...	Other
T1621	Imatinib Mesylate	Imatinib mesylate is a specific tyrosine kinase receptor inhibitor with antineoplasti...	Cancer
T1524	Nilotinib	Nilotinib is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinas...
T1448L	Dasatinib monohydrate	Dasatinib is an orally bioavailable synthetic small molecule-inhibitor of SRC-family ...	Cancer
T0152	Bosutinib	Bosutinib is a synthetic quinolone derivative and dual kinase inhibitor that targets ...	Cancer
T6311	Bafetinib	Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5...	Cancer
T6300	Degrasyn	Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UC...	Cancer

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