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Anti-SHH Antibody (6B515)
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Catalog No. TMAY-00714
Alias sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik
Anti-SHH Antibody (6B515) is a Mouse antibody targeting SHH. Anti-SHH Antibody (6B515) can be used in ELISA.
Anti-SHH Antibody (6B515)
Anti-SHH Antibody (6B515)
😃Good
Catalog No. TMAY-00714Alias sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik
Anti-SHH Antibody (6B515) is a Mouse antibody targeting SHH. Anti-SHH Antibody (6B515) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SHH Antibody (6B515) is a Mouse antibody targeting SHH. Anti-SHH Antibody (6B515) can be used in ELISA. |
| Alias | sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6B515 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SHH / Sonic hedgehog (rh SHH / Sonic hedgehog; TMPY-02832; Q15465; Met1-Gly197). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein that is vital in guiding the early embryo. It has been associated as the major inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Sonic HedgeHog intercellular signal is essential for a various patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Sonic HedgeHog binds to the patched receptor, which functions in association with smoothened, to activate the transcription of target genes. In the absence of sonic HedgeHog, patched receptor represses the constitutive signaling activity of smoothened. Sonic HedgeHog also regulates another factor, the gli oncogene. Defects in sonic hedgehog can cause microphthalmia isolated with coloboma type 5, triphalangeal thumb-polysyndactyly syndrome and holoprosencephaly type 3. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SHH / Sonic hedgehog Protein (TMPY-02832) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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