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Anti-mouse CD86 Antibody (1E806)
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Catalog No. TMAB-08955
Anti-mouse CD86 Antibody (1E806) is a Rat antibody targeting mouse CD86. Anti-mouse CD86 Antibody (1E806) can be used in FCM,WB.
Anti-mouse CD86 Antibody (1E806)
Anti-mouse CD86 Antibody (1E806)
😃Good
Catalog No. TMAB-08955
Anti-mouse CD86 Antibody (1E806) is a Rat antibody targeting mouse CD86. Anti-mouse CD86 Antibody (1E806) can be used in FCM,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $353 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-mouse CD86 Antibody (1E806) is a Rat antibody targeting mouse CD86. Anti-mouse CD86 Antibody (1E806) can be used in FCM,WB. |
| Ig Type | Rat IgG2a, k |
| Clone | 1E806 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | FCM: 1μg/Test; WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed by activated B-lymphocytes and monocytes. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]. |
| Gene Name | CD86 |
| Gene ID | |
| Protein Name | T-lymphocyte activation antigen CD86 |
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
| Molecular Weight | Theoretical: 31 kDa. Actual: 72-74 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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