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Anti-HP1 gamma Antibody (7G984)

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Catalog No. TMAB-07268

Anti-HP1 gamma Antibody (7G984) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (7G984) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-HP1 gamma Antibody (7G984)

Anti-HP1 gamma Antibody (7G984)

😃Good
Catalog No. TMAB-07268
Anti-HP1 gamma Antibody (7G984) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (7G984) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 μg$1,0577-10 days7-10 days
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HP1 gamma Antibody (7G984) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (7G984) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
7G984
Reactivity
Human,Rat (predicted:Mouse)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationNucleus (Potential). Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential).
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Antigen Details
Immunogen
Recombinant Protein: human HP1 gamma Protein
Antigen Species
Human
Gene Name
CBX3
Gene ID
11335
Protein Name
Chromobox protein homolog 3
Uniprot ID
Q13185
Function
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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