Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
Description | WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM). |
Targets&IC50 | BCL-XL:1.1 nM |
In vitro | WEHI-539 hydrochloride is a selective Bcl-XL inhibitor. WEHI-539 augments NSC 241240 induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells[2]. |
Molecular Weight | 620.18 |
Formula | C31H30ClN5O3S2 |
CAS No. | 2070018-33-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (80.62 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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WEHI-539 hydrochloride 2070018-33-4 Apoptosis BCL WEHI-539 Hydrochloride WEHI 539 hydrochloride WEHI539 Hydrochloride WEHI 539 Hydrochloride WEHI539 hydrochloride inhibitor inhibit