Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 118.00 | |
5 mg | In stock | $ 288.00 | |
10 mg | In stock | $ 449.00 | |
25 mg | In stock | $ 739.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,390.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 298.00 |
Description | VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. |
Targets&IC50 | GIRK1/2:165 nM(EC50) , GIRK1/4:720 nM(EC50) |
In vivo | Reduced stress‐induced hyperthermia (SIH), a physiological test of anxiolytic efficacy in wild mice, but had no impact in and Kcnj3 (Girk1) ?/? mice. |
Animal Research | Animal Model:Male C57BL/6J mice, Kcnj3?/? siblings female and male C57BL/6J mice. Dosage:10 mg/kg; 30mg/kg. Administration:Intraperitoneal injection |
Molecular Weight | 349.83 |
Formula | C18H21ClFN3O |
CAS No. | 2126040-21-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (714.63 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
VU0810464 2126040-21-7 Membrane transporter/Ion channel Potassium Channel cells KcsA neuronal GIRK HPC VU 0810464 SAN VU-0810464 inhibit Inhibitor inhibitor