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Tocainide hydrochloride

Catalog No. T9234 CAS 71395-14-7

Synonyms: 2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride,

Tocainide hydrochloride is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.

Tocainide hydrochloride, CAS 71395-14-7

Pack Size	Availability	Price/USD
1 mg	In stock	138.00
5 mg	In stock	308.00
10 mg	In stock	462.00
25 mg	In stock	833.00
50 mg	In stock	1251.00
100 mg	In stock	1876.00

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Purity 98.85%

HNMR HPLC COA

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tocainide hydrochloride is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.
In vitro	Tocainide hydrochloride effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide hydrochloride infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity[1].

Synonyms	2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride ,
Purity	98.85%
Molecular Weight	228.72
Formula	C11H17ClN2O
CAS No.	71395-14-7

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23. 2. De Luca A,et al.Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.Mol Pharmacol. 2003 Oct;64(4):932-45.

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