Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 37.00 | |
10 mg | In stock | $ 50.00 | |
50 mg | In stock | Inquiry | |
1 mL * 10 mM (in DMSO) | In stock | $ 51.00 |
Description | Tiagabine (NO050328) is an Anti-epileptic Agent. The physiologic effect of tiagabine is by means of Decreased Central Nervous System Disorganized Electrical Activity. |
In vitro | Tiagabine is a potent inhibitor of GABA uptake into neurons and glial cells. It is involved in modulating GABA levels, especially in areas such as the hippocampus and thalamus[2]. Tiagabine not only affected the decay kinetics of the IPSCs, it also reduced the frequency of occurrence of both spontaneous and miniature IPSCs[1]. |
In vivo | Tiagabine offers a significant neuroprotection in global ischemia in gerbils when given 30 min before ischemia but not when given 3 h after ischemia[3]. |
Synonyms | TGB, NO050328, Gabitril, NO328 |
Molecular Weight | 375.55 |
Formula | C20H25NO2S2 |
CAS No. | 115103-54-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (26.63 mM)
You can also refer to dose conversion for different animals. More
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Tiagabine 115103-54-3 Membrane transporter/Ion channel Neuroscience GABA Receptor NO 050328 Gamma-aminobutyric acid Receptor TGB NO050328 Inhibitor inhibit γ-Aminobutyric acid Receptor Gabitril NO-328 NO 328 NO328 NO-050328 inhibitor