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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4071 | Repotrectinib | TPX-0005 , TPX 0005 , TPX0005 | ROS , Src , ALK , ROS Kinase , Trk receptor |
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively. |