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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1779 | SAG | Smoothened Agonist (SAG) HCl , Smoothened Agonist | Hedgehog/Smoothened , Smo |
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway. |