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S- (+)-Rolipram

Catalog No. T6649    CAS 85416-73-5    Synonyms: (S)-Rolipram, (+)-Rolipram, (S)-(+)-Rolipram

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Pack Size Availability Price/USD Quantity
5 mg Inquiry 51.00
10 mg Inquiry 88.00
25 mg Inquiry 198.00
50 mg Inquiry 345.00
100 mg Inquiry 621.00
1 mL * 10 mM (in DMSO) Inquiry 51.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Receptor:

PDE4;

Chemical Information:
Molecular Weight 275.34
Formula C16H21NO3
CAS Number 85416-73-5
Solubility

DMSO: 27.5 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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