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S- (+)-Rolipram

Catalog No. T6649    CAS 85416-73-5    Synonyms: (S)-Rolipram, (+)-Rolipram, (S)-(+)-Rolipram

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Pack Size Availability Price/USD Quantity
5 mg Inquiry 65.00
10 mg Inquiry 110.00
25 mg Inquiry 250.00
50 mg Inquiry 455.00
100 mg Inquiry 790.00
1 mL * 10 mM (in DMSO) Inquiry 65.00
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Biological Activity:

Product Description:

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Receptor:

PDE4;

Chemical Information:
Molecular Weight 275.34
Formula C16H21NO3
CAS Number 85416-73-5
Solubility

DMSO: 27.5 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.