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Home > Neuroscience > Gamma-secretase > PF-03084014

PF-03084014

Catalog No. T6935    CAS 1290543-63-3    Synonyms: PF03084014, PF 03084014, Nirogacestat, PF-3084014

PF-03084014 (PF-3084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).

Pack Size Availability Price/USD Quantity
2 mg In stock 50.00
5 mg In stock 90.00
10 mg In stock 150.00
25 mg In stock 330.00
50 mg In stock 600.00
1 mL * 10 mM (in DMSO) In stock 90.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

PF-03084014 (PF-3084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).

Receptor:

γ secretase;

Chemical Information:
Molecular Weight 489.64
Formula C27H41F2N5O
CAS Number 1290543-63-3
Solubility

DMSO: 90 mg/mL (183.8 mM)

Ethanol: 90 mg/mL (183.8 mM)

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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