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Search Results for " pd-l1 inhibitor 1 "

Targets

78

Compounds

1728

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3655 BMS-1 PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1 Apoptosis , PD-1/PD-L1
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ...
T3146 BMS-202 PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2 Apoptosis , PD-1/PD-L1
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.
T9616 PD-1/PD-L1-IN-10 PD-1/PD-L1
PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.
T4696 BMS202 hydrochloride (1675203-84-5(free base)) PD-1/PD-L1 inhibitor 2 hydrochloride PD-1/PD-L1
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L...
T26859 BMS-8 PD-1/PD-L1
BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.
T39591 Human PD-L1 inhibitor I Human PD-L1 inhibitor I
Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 i...
T39588 Human PD-L1 inhibitor IV Human PD-L1 inhibitor IV
Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 μM and effectively blocks the interaction between hPD-1 and hPD-L1.
T39589 Human PD-L1 inhibitor III Human PD-L1 inhibitor III
Human PD-L1 inhibitor III is a human PD-L1 inhibitor.
T39590 Human PD-L1 inhibitor II Human PD-L1 inhibitor II
Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.
T36899 INCB086550 PD-1/PD-L1-IN-8 PD-1/PD-L1
INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.
T83976 ARB-272572 hydrochloride ARB-272572 hydrochloride(2368182-63-0 Free base) PD-1/PD-L1
ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1/PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1/PD-L1 cell signaling by inducing homologous interactions with PD-L1 pro...
T36487 Evixapodlin PD-1/PD-L1-IN 7,GS-4224 Antiviral , HBV , PD-1/PD-L1
Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.
T5697 BMS-1166 PD-1/PD-L1
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
T10565 BMS-1001 hydrochloride PD-1/PD-L1
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat...
T9651 PD-1/PD-L1-IN-9 PD-1/PD-L1
PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells' ability to kill tumor cells and demonstrates significant antitumor activity in...
T12379 PD-1-IN-22 Others , PD-1/PD-L1
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).
T8470 BMS-1001 PD-1/PD-L1
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
T40111L BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride PD-1/PD-L1
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...
T76750 Cemiplimab REGN-2810,SAR-439684 Others
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...
T3468 Tomivosertib eFT508 MNK , PD-1/PD-L1
Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.
T12380 PD-1/PD-L1-IN 5 TFA PD-1/PD-L1-IN 5 Others
PD-1/PD-L1-IN 5 is an inhibitor of PD-1/PD-L1 protein/protein interaction (IC50 of ≤100 nM).
T23805 BMS-242 BMS242
BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.
T61929 PD-1/PD-L1-IN-14
PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM). By inhibiting the interaction of PD-1/PD-L1, PD-1/PD-L1-IN-14 promotes dimerization, endocytosis and degradation of PD-L1.
T70286 BMS-37
BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.
T63607 PD-1/PD-L1-IN-22
PD-1/PD-L1-IN-22 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interactions that blocks PD-1/PD-L1 interactions (IC50: 0.732 μM). PD-1/PD-L1-IN-22 can be used to study cancer, infectious diseases and autoim...
T62193 PD-1/PD-L1-IN 5
PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).
T72670 PD-1/PD-L1-IN-13
PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-cell activation and delays tumour growth in a Hepa1-6 homozyg...
T36900 PD-1/PD-L1-IN-NP19 PD-1/PD-L1-IN-NP19 PD-1/PD-L1
PD-1/PD-L1-IN-NP19, a PD-1/PD-L1 inhibitor, exhibits an IC50 of 12.5 nM against the human PD-1/PD-L1 interaction, potentially activating the tumor immune microenvironment and contributing to its antitumor effects[1].
T63329 PD-1/PD-L1-IN-25
PD-1/PD-L1-IN-25 is an inhibitor of PD-1/PD-L1 interaction (IC50: 16.17 nM) that effectively activates anti-tumor immunity of T cells in PBMCs. PD-1/PD-L1-IN-25 can be used to study cancer.
T64086 PD-1/PD-L1-IN-20
PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks the PD-1/PD-L1 interaction (IC50: 5.29 nM). PD-1/PD-L1-IN-20 can be used to study cancer, infectious disea...
T72724 PD-1/PD-L1-IN-30
PD-1/PD-L1-IN-30 is a PD-1/PD-L1 binding inhibitor, with an IC 50 value of 0.018 μM. PD-1/PD-L1-IN-30 can be used for research of cancers and other related diseases .
T63614 PD-1/PD-L1-IN-15
PD-1/PD-L1-IN-15 is a potent inhibitor of PD-1/PD-L1 (IC50: 60.1 nM) and has shown investigational potential for tumor immunotherapy.
T62501 PD-1/PD-L1-IN-17
PD-1/PD-L1-IN-17 (Compound P20) is a potent PD-1/PD-L1 inhibitor (IC50: 26.8 nM). PD-1/PD-L1-IN-17 is a promising lead compound for the development of inhibitors of PD-1/PD-L1 interactions. -17 has potential for cancer d...
T63948 PD-1/PD-L1-IN-16
PD-1/PD-L1-IN-16 is a potent inhibitor of PD-1/PD-L1 (IC50: 53.2 nM) and has shown research potential for tumour immunotherapy.
T14670 BMS-1166 hydrochloride Others
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immun...
T72721 PD-1/PD-L1-IN-29
PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM. It effectively binds to PD-L1, inhibiting the PD-1/PD-L1 interaction, promotes PD-L1 dimerization and its interna...
T70285 BMS-200
BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.
T69447 APBC
APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-...
T61968 PD-1/PD-L1-IN 6
PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1...
T76080 Human PD-L1 inhibitor V PD-1/PD-L1
Human PD-L1 Inhibitor V is a peptide that binds to the human PD-1 protein with an affinity characterized by a dissociation constant (Kd) of 3.32 μM, effectively inhibiting the hPD-1/hPD-L1 interaction [1].
T72675 PD-1/PD-L1-IN-23
PD-1/PD-L1-IN-23 is a potent, orally active ester prodrug of L7, a benzooxadiazole derivative, and functions as an inhibitor of PD-1/PD-L1. It has been biologically evaluated for its inhibitory effects on PD-L1, demonstr...
T79314 PD-L1-IN-3 PD-1/PD-L1
PD-L1-IN-3 (Compound 4a) functions as an inhibitor targeting the PD-1/PD-L1 axis, with an IC50 value of 4.97nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1...
T79643 PD-1/PD-L1-IN-33 PD-1/PD-L1
PD-1/PD-L1-IN-33 (Compound N11), a PD-1/PD-L1 inhibitor, effectively impedes the interaction between PD-1 and PD-L1 with an IC50 of 6.3 nM. By doing so, it enhances T-cell proliferation, activation, and infiltration with...
T72691 PD-1/PD-L1-IN-28
PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity. This immune checkpoint inhibitor effectively blocks the interaction with...
T82960 ASC-69 APY69 PD-1/PD-L1
ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].
T73642 PD-1/PD-L1-IN 3 TFA
PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, serves as a potent and selective inhibitor of PD-1/PD-L1 interaction. This compound disrupts PD-L1's binding with PD-1 and CD80 by directly binding to PD-L1, exhibiting IC50 va...
T72668 PD-1/PD-L1-IN-26 PD-1/PD-L1
PD-1/PD-L1-IN-26 (Compound II-14) is a potent PD-1/PD-L1 inhibitor, demonstrating an IC50 of 0.0380 μM. It enhances the immune microenvironment by facilitating CD4+ T cell infiltration into tumor tissues, indicating pote...
T72680 PD-1/PD-L1-IN-27 PD-1/PD-L1
PD-1/PD-L1-IN-27 is a potent inhibitor of PD-1/PD-L1, exhibiting an IC50 of 134 nM and demonstrating antitumor effects with minimal T cell cytotoxicity. It activates CD8+ T cells and mitigates T cell exhaustion [1].
T61574 PD-L1-IN-1
PD-L1-IN-1, a powerful PD-L1 inhibitor, demonstrated an IC50 of 115 nM. By forming a robust bond with the PD-L1 protein, PD-L1-IN-1 effectively suppressed tumor growth by enhancing the antitumor immune activity of periph...
TP1960 (D)-PPA 1
PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.

Compounds

BMS-1
T3655
Synonym: PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1
Target: Apoptosis, PD-1/PD-L1
BMS-202
T3146
Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2
Target: Apoptosis, PD-1/PD-L1
PD-1/PD-L1-IN-10
T9616
Synonym:
Target: PD-1/PD-L1
BMS202 hydrochloride (1675203-84-5(free base))
T4696
Synonym: PD-1/PD-L1 inhibitor 2 hydrochloride
Target: PD-1/PD-L1
BMS-8
T26859
Synonym:
Target: PD-1/PD-L1
Human PD-L1 inhibitor I
T39591
Synonym: Human PD-L1 inhibitor I
Target:
Human PD-L1 inhibitor IV
T39588
Synonym: Human PD-L1 inhibitor IV
Target:
Human PD-L1 inhibitor III
T39589
Synonym: Human PD-L1 inhibitor III
Target:
Human PD-L1 inhibitor II
T39590
Synonym: Human PD-L1 inhibitor II
Target:
INCB086550
T36899
Synonym: PD-1/PD-L1-IN-8
Target: PD-1/PD-L1
ARB-272572 hydrochloride
T83976
Synonym: ARB-272572 hydrochloride(2368182-63-0 Free base)
Target: PD-1/PD-L1
Evixapodlin
T36487
Synonym: PD-1/PD-L1-IN 7,GS-4224
Target: Antiviral, HBV, PD-1/PD-L1
BMS-1166
T5697
Synonym:
Target: PD-1/PD-L1
BMS-1001 hydrochloride
T10565
Synonym:
Target: PD-1/PD-L1
PD-1/PD-L1-IN-9
T9651
Synonym:
Target: PD-1/PD-L1
PD-1-IN-22
T12379
Synonym:
Target: Others, PD-1/PD-L1
BMS-1001
T8470
Synonym:
Target: PD-1/PD-L1
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
T40111L
Synonym:
Target: PD-1/PD-L1
Cemiplimab
T76750
Synonym: REGN-2810,SAR-439684
Target: Others
Tomivosertib
T3468
Synonym: eFT508
Target: MNK, PD-1/PD-L1
PD-1/PD-L1-IN 5 TFA
T12380
Synonym: PD-1/PD-L1-IN 5
Target: Others
BMS-242
T23805
Synonym: BMS242
Target:
PD-1/PD-L1-IN-14
T61929
Synonym:
Target:
BMS-37
T70286
Synonym:
Target:
PD-1/PD-L1-IN-22
T63607
Synonym:
Target:
PD-1/PD-L1-IN 5
T62193
Synonym:
Target:
PD-1/PD-L1-IN-13
T72670
Synonym:
Target:
PD-1/PD-L1-IN-NP19
T36900
Synonym: PD-1/PD-L1-IN-NP19
Target: PD-1/PD-L1
PD-1/PD-L1-IN-25
T63329
Synonym:
Target:
PD-1/PD-L1-IN-20
T64086
Synonym:
Target:
PD-1/PD-L1-IN-30
T72724
Synonym:
Target:
PD-1/PD-L1-IN-15
T63614
Synonym:
Target:
PD-1/PD-L1-IN-17
T62501
Synonym:
Target:
PD-1/PD-L1-IN-16
T63948
Synonym:
Target:
BMS-1166 hydrochloride
T14670
Synonym:
Target: Others
PD-1/PD-L1-IN-29
T72721
Synonym:
Target:
BMS-200
T70285
Synonym:
Target:
APBC
T69447
Synonym:
Target:
PD-1/PD-L1-IN 6
T61968
Synonym:
Target:
Human PD-L1 inhibitor V
T76080
Synonym:
Target: PD-1/PD-L1
PD-1/PD-L1-IN-23
T72675
Synonym:
Target:
PD-L1-IN-3
T79314
Synonym:
Target: PD-1/PD-L1
PD-1/PD-L1-IN-33
T79643
Synonym:
Target: PD-1/PD-L1
PD-1/PD-L1-IN-28
T72691
Synonym:
Target:
ASC-69
T82960
Synonym: APY69
Target: PD-1/PD-L1
PD-1/PD-L1-IN 3 TFA
T73642
Synonym:
Target:
PD-1/PD-L1-IN-26
T72668
Synonym:
Target: PD-1/PD-L1
PD-1/PD-L1-IN-27
T72680
Synonym:
Target: PD-1/PD-L1
PD-L1-IN-1
T61574
Synonym:
Target:
(D)-PPA 1
TP1960
Synonym:
Target:
1 2

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc) Human HEK293
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-05239 HER2/ERBB2 Protein, Human, Recombinant , Biotinylated Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01226 CD4 Protein, Mouse, Recombinant (His) Mouse HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01023 CD38 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-02031 B7-H3 Protein, Human, Recombinant (His) Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-01050 Cadherin 6/CDH6 Protein, Human, Recombinant (His) Human HEK293
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-01608 Decorin Protein, Human, Recombinant (His) Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-02099 CD63 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02034 Siglec-2/CD22 Protein, Human, Recombinant (His) Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His) Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05208 PD-L1 Protein, Human, Recombinant Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-01853 SIRP gamma Protein, Human, Recombinant (His) Human HEK293
Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunog...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His) Human HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01283 Glypican 3/GPC3 Protein, Human, Recombinant (His) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-01851 CD73 Protein, Human, Recombinant (His) Human HEK293
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-01938 CD98 Protein, Human, Recombinant (His) Human HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-00991 LIFR Protein, Human, Recombinant (His) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-04949 PD-L1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04698 HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01305 OSMR Protein, Human, Recombinant (His) Human HEK293
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His) Human HEK293
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
TMPY-03958 TGF alpha Protein, Human, Recombinant Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-05016 HHLA2 Protein, Human, Recombinant (His) Human HEK293
B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these ...
TMPY-03383 IL-7 Protein, Human, Recombinant Human E. coli
IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progeni...
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus-Insect Cells
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate...
TMPY-01963 IL-21 Protein, Human, Recombinant Human E. coli
IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellul...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481 IL-1R2 Protein, Human, Recombinant Human HEK293
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-01151 MXRA8 Protein, Human, Recombinant (His) Human HEK293
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi) Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi) Human HEK293
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
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AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
CD155/PVR Protein, Human, Recombinant (hFc)
TMPY-00699
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant
TMPY-00399
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant , Biotinylated
TMPY-05239
Species: Human
Expression System: HEK293
CD4 Protein, Mouse, Recombinant (His)
TMPY-01226
Species: Mouse
Expression System: HEK293
CD38 Protein, Human, Recombinant (His)
TMPY-01023
Species: Human
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
B7-H3 Protein, Human, Recombinant (His)
TMPY-02031
Species: Human
Expression System: HEK293
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
TMPY-01050
Species: Human
Expression System: HEK293
Decorin Protein, Human, Recombinant (His)
TMPY-01608
Species: Human
Expression System: HEK293
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293
CD63 Protein, Human, Recombinant (His)
TMPY-02099
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His)
TMPY-02034
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant
TMPY-05208
Species: Human
Expression System: HEK293
SIRP gamma Protein, Human, Recombinant (His)
TMPY-01853
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
CD30/TNFRSF8 Protein, Human, Recombinant (His)
TMPY-01827
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (His)
TMPY-01283
Species: Human
Expression System: HEK293
CD73 Protein, Human, Recombinant (His)
TMPY-01851
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
TMPY-01462
Species: Human
Expression System: HEK293
CD98 Protein, Human, Recombinant (His)
TMPY-01938
Species: Human
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (His)
TMPY-00991
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant (His), Biotinylated
TMPY-04949
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)
TMPY-04698
Species: Human
Expression System: HEK293
OSMR Protein, Human, Recombinant (His)
TMPY-01305
Species: Human
Expression System: HEK293
LILRB5/CD85c Protein, Human, Recombinant (His)
TMPY-04826
Species: Human
Expression System: HEK293
TGF alpha Protein, Human, Recombinant
TMPY-03958
Species: Human
Expression System: E. coli
HHLA2 Protein, Human, Recombinant (His)
TMPY-05016
Species: Human
Expression System: HEK293
IL-7 Protein, Human, Recombinant
TMPY-03383
Species: Human
Expression System: E. coli
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus-Insect Cells
Neurotrophin 3 Protein, Human, Recombinant
TMPY-04069
Species: Human
Expression System: E. coli
IL-21 Protein, Human, Recombinant
TMPY-01963
Species: Human
Expression System: E. coli
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
IL-1R2 Protein, Human, Recombinant
TMPY-03481
Species: Human
Expression System: HEK293
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
MXRA8 Protein, Human, Recombinant (His)
TMPK-01151
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi)
TMPK-01074
Species: Human
Expression System: HEK293
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
TMPK-00383
Species: Human
Expression System: HEK293
TargetMol