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Endocrinology/Hormones Opioid Receptor Naloxone hydrochloride

Naloxone hydrochloride

Catalog No. T0102   CAS 357-08-4
Synonyms: Naloxone HCl
Purity 99.80% Datasheet

Naloxone hydrochloride is a specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.

Naloxone hydrochloride, CAS 357-08-4
Pack Size Availability Price/USD Quantity
25 mg In stock 50.00
50 mg In stock 73.00
100 mg In stock 109.00
200 mg In stock 197.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Naloxone hydrochloride is a specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
Targets&IC50 Opioid Receptor,  
Animal Research
Animal Model: rats
Synonyms Naloxone HCl
Purity 99.80%
Appearance solid
Molecular Weight 363.84
Formula C19H21NO4·HCl
CAS No. 357-08-4

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 197.9 mM

Water: 197.9 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Liu B, et al. J Pharmacol Exp Ther, 2000, 293(2), 607-617. 2. Froehlich JC, et al. Pharmacol Biochem Behav, 1990, 35(2), 385-390. 3. Gallate JE, et al. Psychopharmacology (Berl), 1999, 142(3), 302-308. 4. Liu B, et al. J Pharmacol Exp Ther, 2000, 295(1), 125-132.

Related Compound Libraries

This product is contained In the following compound libraries:
Approved Drug Library Bioactive Compound Library FDA-approved Drug Library

Related Products

Related compounds with same targets
Naloxone hydrochloride Mirtazapine Meptazinol hydrochloride Loperamide hydrochloride Dextromethorphan HBr monohydrate Progesterone Mianserin hydrochloride Trimebutine

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.