Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NPD1335 is a potent Trypanosoma brucei phosphodiesterase B1 ( TbrPDEB1 ) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 shows a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | NPD1335 is a potent Trypanosoma brucei phosphodiesterase B1 ( TbrPDEB1 ) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 shows a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death [1]. |
Targets&IC50 | TbrPDEB1:6.9, NPD-1335:6.2(pIC50) |
Molecular Weight | 455.55 |
Formula | C28H29N3O3 |
CAS No. | 2376326-31-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NPD-1335 2376326-31-5 Others NPD 1335 NPD1335 inhibitor inhibit