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Mezlocillin Sodium

Catalog No. T6582 CAS 42057-22-7

Synonyms: Baycipen

Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.

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Mezlocillin Sodium, CAS 42057-22-7

Pack Size	Availability	Price/USD
25 mg	In stock	$ 36.00
50 mg	In stock	$ 51.00
100 mg	In stock	$ 75.00
200 mg	In stock	$ 108.00
500 mg	In stock	$ 183.00
1 mL * 10 mM (in DMSO)	In stock	$ 53.00

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Purity: 95.93%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Mezlocillin Sodium (Baycipen) is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.

In vitro

Mezlocillin sodium has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of mezlocillin results from the inhibition of cell wall synthesis and is mediated through mezlocillin binding to penicillin binding proteins (PBPs). Mezlocillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Mezlocillin inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that mezlocillin interferes with an autolysin inhibitor. Unlike many other penicillins, mezlocillin is either extensively metabolized or is subject to biliary excretion, as only about 50% of the dose is accounted for in normal urine. [1]

Synonyms	Baycipen
Molecular Weight	561.56
Formula	C21H25N5O8S2·Na
CAS No.	42057-22-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 92 mg/mL (163.8 mM)

DMSO: 93 mg/mL (165.6 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. McCloskey RV, et al. Pharmacotherapy, 1982, 2(6), 300-312.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Infection Compound Library Immunology/Inflammation Compound Library Covalent Inhibitor Library FDA-Approved & Pharmacopeia Drug Library Anti-Bacterial Compound Library Bioactive Compound Library Approved Drug Library Bioactive Compounds Library Max Antibiotics Library

Related Products

Related compounds with same targets

Cefazedone Chlorprothixene hydrochloride Ampicillin Camalexin Sulfasalazine Prulifloxacin 4(3H)-Quinazolinone D-(+)-Melezitose hydrate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Mezlocillin Sodium 42057-22-7 Microbiology/Virology Antibiotic Antibacterial BAY-f 1353 bacterial infection gram-positive bacteria Mezlocillin Baycipen gram-negative bacteria Bacterial inhibit Inhibitor inhibitor

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