store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MS645 is an inhibitor of bromodomain-containing protein 4 (BRD4) with a Ki of 18.4 nM for BRD4-BD1/BD2.
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Description | MS645 is an inhibitor of bromodomain-containing protein 4 (BRD4) with a Ki of 18.4 nM for BRD4-BD1/BD2. |
Targets&IC50 | BRD4 BD1/2:18.4 nM (ki) |
In vitro | MS645 blocks the proliferation of triple-negative breast cancer (TNBC) cells. MS645 down-regulates proinflammatory cytokines and genes for cell-cycle control and DNA damage repair that are largely unaffected by monovalent BRD inhibition[1]. |
Molecular Weight | 938.04 |
Formula | C48H54Cl2N10O2S2 |
CAS No. | 2250091-96-2 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 180 mg/mL (191.9 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MS645 2250091-96-2 Chromatin/Epigenetic Epigenetic Reader Domain MS 645 MS-645 inhibitor inhibit