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LYN-1604 dihydrochloride

Catalog No. T8808L CAS 2310109-38-5

Synonyms: LYN-1604 2HCl（2216753-86-3 free base)

LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.

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LYN-1604 dihydrochloride Chemical Structure

LYN-1604 dihydrochloride, CAS 2310109-38-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 48.00
2 mg	In stock	$ 71.00
5 mg	In stock	$ 118.00
10 mg	In stock	$ 198.00
25 mg	In stock	$ 372.00
50 mg	In stock	$ 556.00
100 mg	In stock	$ 783.00
500 mg	In stock	$ 1,650.00
1 mL * 10 mM (in DMSO)	In stock	$ 172.00

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Purity: 99.80%

Purity: 98.95%

Biological Description

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Storage & Solubility Information

Description	LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
Targets&IC50	ULK1:18.94 nM (EC50)
In vitro	LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo

Synonyms	LYN-1604 2HCl（2216753-86-3 free base)
Molecular Weight	657.54
Formula	C33H45Cl4N3O2
CAS No.	2310109-38-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (38.02 mM)

References and Literature

1. Zhang L , Fu L , Zhang S , et al. Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo[J]. Chemical Science, 2017, 8(4):2687.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Kinase Inhibitor Library Bioactive Compound Library NO PAINS Compound Library Apoptosis Compound Library Autophagy Compound Library Anti-Breast Cancer Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max

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Keywords

LYN-1604 dihydrochloride 2310109-38-5 Apoptosis Autophagy anti-tumor Unc-51 like kinase negative cancer LYN-1604 2HCl breast ULK1 LYN1604 Dihydrochloride ULK 2216753-86-3 free base LYN 1604 Dihydrochloride Inhibitor LYN1604 2216753-86-3 LYN1604 dihydrochloride LYN 1604 dihydrochloride activator TNBC LYN-1604 triple LYN-1604 2HCl（2216753-86-3 free base) LYN-1604 Dihydrochloride LYN 1604 inhibit inhibitor

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