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Impurity F of Calcipotriol

Catalog No. T11646   CAS 112875-61-3

Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

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Impurity F of Calcipotriol Chemical Structure
Impurity F of Calcipotriol, CAS 112875-61-3
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.
In vitro Calcipotriol exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25, and mouse WEHI-3 cancer cell lines.
Molecular Weight 641.13
Formula C39H68O3Si2
CAS No. 112875-61-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Binderup (1993) Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: effects on cell growth regulation in vitro and calcium metabolism in vivo. Pharmacol.Toxicol. 72 240. 2. Knutson et al (1997) Pharmacokinetics and systemic effect on calcium homeostasis of 1a,24-dihydroxyvitamin D2 in rats. Biochem.Pharmacol. 53 829. 3. Wietrzyk et al (2007) Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anticancer Drugs 18 447.111 4. Lise Binderup,, Erik Bramm. Effects of a novel vitamin D analogue MC 903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo. Biochemical Pharmacology. Volume 37, Issue 5, 1 March 1988, Pages 889-895

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Impurity F of Calcipotriol 112875-61-3 Others inhibitor inhibit

 

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