1808
353
77
3
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10525 | SCD1 inhibitor-4 | Dehydrogenase , Stearoyl-CoA Desaturase (SCD) | |
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes. | |||
T67767 | HIF-1 inhibitor-4 | HIF-1 inhibitor-4 | HIF |
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level. | |||
T36527 | IL-4-inhibitor-1 | IL Receptor | |
IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhib... | |||
T2457 | IRAK-1-4 Inhibitor I | IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor | IRAK |
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1. | |||
T67698 | P53-Mdm2 inhibitor 4 | Mdm2 , p53 | |
p53-Mdm2 inhibitor 4 inhibits the p53-MDM2 protein-protein interaction. | |||
T9262 | MAT2A inhibitor 4 | Others , Methionine Adenosyltransferase (MAT) | |
MAT2A inhibitor 4 is an inhibitor of the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A) and can be used for the research of cancer. | |||
T9631 | IRAK-4 protein kinase inhibitor 2 | IRAK | |
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). | |||
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T77341 | GSK-3 inhibitor 4 | GSK-3 , CDK | |
GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with IC50 values of 0.56 nM, 0.45 nM, 0.47 μM, 0.68 μM, respect... | |||
T21954 | EGFR/ErbB-2/ErbB-4 inhibitor-2 | EGFR/ErbB2 Inhibitor | EGFR |
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively) | |||
T36018 | Phosphodiesterase 4 Inhibitor | ||
Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme. | |||
T39574 | RIP2 Kinase Inhibitor 4 | ||
RIP2 Kinase Inhibitor 4 is a highly potent and selective RIPK2 PROTAC compound that efficiently degrades RIPK2 (with a pIC50 value of 8) and effectively inhibits the release of TNF-α. | |||
T65816 | Prolyl-4-hydroxylase Inhibitor 11 | Others | |
Prolyl-4-hydroxylase Inhibitor 11, a novel proline 4-hydroxylase inhibitor, shows protective effects against oxidative stress and Cu(II) toxicity in Chlorella vulgaris. | |||
T11672 | IRAK inhibitor 4 | Others | |
IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor. | |||
T11772 | KRAS inhibitor-4 | Others | |
KRAS inhibitor-4 developed as anticancer agents, is a potent KRAS inhibitor. | |||
T4245 | IWP-4 | Inhibitor of Wnt Production-4 | Wnt/beta-catenin |
IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor. | |||
T3156 | Ciliobrevin A | Hedgehog Pathway Inhibitor 4,HPI-4 | Hedgehog/Smoothened |
Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM. | |||
T12002 | Menin-MLL inhibitor 4 | Others | |
Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction . | |||
T77716 | Wnt pathway inhibitor 4 | Antibacterial | |
Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells. | |||
T11779 | KRas G12C inhibitor 4 | Ras | |
KRas G12C inhibitor 4 is a compound that inhibits KRas G12C. | |||
T61147 | Chitin synthase inhibitor 4 | Antibiotic | |
Chitin synthase inhibitor 4 is a chitin synthase (CHS) inhibitor with antimicrobial activity.Chitin synthase inhibitor 4 is a CHS-based compound and a candidate fungicide. | |||
T11423 | Glutaminyl Cyclase Inhibitor 4 | Others | |
Glutaminyl Cyclase Inhibitor 4 is a potent, selective glutaminyl cyclase (QC) inhibitor (IC50: 6.1 nM). It is a potent anti-Alzheimer’s agent. | |||
T11671 | IRAK inhibitor 4 trans | SGLT | |
IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers... | |||
T19140 | 4-Propionamidophenol | Others | |
4-Propionamidophenol is a kind of analog of p-acetamidophenol. | |||
T7084 | 2-Bromo-4'-hydroxyacetophenone | SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide | Phosphatase |
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH... | |||
T11568 | HIV-1 integrase inhibitor 4 | Others | |
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM). | |||
T4596 | 4-IBP | Sigma receptor | |
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) . | |||
T11299 | FLT3-IN-4 | FLT3 inhibitor 9u | FLT |
FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenous leukemia. | |||
T62083 | Camonsertib | ATR inhibitor 4,RP-3500 | ATM/ATR |
Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR... | |||
T9061 | EN4 | EN4 MYC inhibitor | c-Myc |
EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, an... | |||
T36758 | CAIX Inhibitor S4 | S4 | Carbonic Anhydrase |
CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM. | |||
T22195 | CBFβ Inhibitor | 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine | DNA/RNA Synthesis |
CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1. | |||
T77526 | Pim-1 kinase inhibitor 4 | Apoptosis , Pim | |
Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity and potential anticancer activity, and inhibits DPPH.Pim-1 kinase in... | |||
T12277 | NVS-ZP7-4 | Others | |
NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7). | |||
T5938 | 4-Phenoxybenzylamine | HCV Protease | |
4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a . | |||
T8794 | 4-MMPB | 15-Lipoxygenase Inhibitor 1 | Apoptosis , Others , Lipoxygenase |
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxyg... | |||
T6669 | SH-4-54 | STAT | |
SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor. | |||
T4364 | Aftin-4 | Aftin 4,Aftin4 | Beta Amyloid , Gamma-secretase |
Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus... | |||
T39598 | 4-Chlorocatechol | Others | |
4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2]. | |||
T7844 | 4-IPP | 4-Iodo-6-phenylpyrimidine | Others |
4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) | |||
T7568 | LM22A-4 | Trk receptor | |
LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay) | |||
T77554 | GSK-3 Inhibitor 5 | 4-Cyanophenacyl bromide | GSK-3 |
GSK-3 Inhibitor 5 (4-Cyanophenacyl bromide) is a ketone derivative that is used as an intermediate in pharmaceuticals and organic synthesis, and inhibits glycogen synthase kinase 3 (GSK-3). | |||
T10138 | 4-Desmethoxy Omeprazole | Drug Metabolite | |
4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM). | |||
T8748 | Exendin-4 acetate | Glucagon Receptor | |
Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM). | |||
T1365 | Thioisonicotinamide | Pyridine-4-carbothioamide,Isothionicotinamide,4-Pyridylthiocarboxamide | Antibiotic |
Thioisonicotinamide (Isothionicotinamide) is a chemical based on the nicotinamide structure, but in which the amide is in the 4-position and not the 3-position. | |||
T0691 | Sulisobenzone | Benzophenone-4,Sungard | Others |
Sulisobenzone (Sungard) (benzophenone-4), an ingredient in certain sunblocks, protects the skin against damage by short-wave UVA ultraviolet light and UVB. | |||
T8545 | FEN1-IN-4 | FEN1 Inhibitor C2 | Others |
FEN1-IN-4 (FEN1 Inhibitor C2) is an inhibitor of human flap endonuclease-1 (hFEN1) | |||
T3062 | WIKI4 | PARP , Wnt/beta-catenin | |
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2). | |||
T14916 | CDK2-IN-4 | CDK | |
CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A. It shows 2,000-fold selectivity over CDK1/cyclin B with IC50 of 86 uM. | |||
T11471 | GSK-3β inhibitor 2 | 5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy- | GSK-3 |
GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50 = 1.1 nM). GSK-3β inhibitor 2 can be used in studies about Al... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5883 | 4-Ethylphenol | Others , Endogenous Metabolite | |
4-Ethylphenol is a volatile phenolic compound related to off-odour in wine. | |||
T8783 | 4-Methylbiphenyl | 4-Phenyltoluene | Endogenous Metabolite |
4-Methylbiphenyl (4-Phenyltoluene) is a human endogenous metabolite. | |||
T1391 | 4-Methylumbelliferone | Hymecromone,4-MU | Others |
4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITR... | |||
PDK0015 | 4-Hydroxycoumarin | Endogenous Metabolite , Antibacterial , AChR | |
4-Hydroxycoumarin, a coumarin derivative.4-Hydroxycoumarin serves as an immediate precursor of 4-hydroxycoumarin (4HC) type anticoagulants (for example, warfarin). 4-Hydroxycoumarin derivatives are employed as the antic... | |||
T8260 | 4',5-Dihydroxyflavone | Lipoxygenase , Glucosidase | |
4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM). | |||
T5716 | 4'-Methoxyresveratrol | 4'-O-Methylresveratrol | advanced glycation end products |
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product form the roots of Rheum palmatum L,has significant hypoglycemic, anti-inflammatory, and antioxidant effects.4'-Methoxyresveratrol alleviates AGE-induced... | |||
T21095 | 4-Hydroxybenzylamine | 4-(Aminomethyl)phenol,4-HOBA | Endogenous Metabolite |
4-Hydroxybenzylamine (4-HOBA) is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension. | |||
T7456 | 4-Ethyloctanoic acid | Others | |
4-Ethyloctanoic acid is a natural product isolated from Saussurea lappa Clarke,acts as food additive,Industrial perfume,and so on. | |||
TN1274 | 4-Allylcatechol | 4-Allylpyrocatechol,Hydroxychavicol | Others |
4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ... | |||
TN1278 | 4'-Methoxypuerarin | Others | |
4'-Methoxypuerarin is a natural product isolated from Pueraria lobata. | |||
TMO2713 | 4(3H)-Quinazolinone | Quinazolin-4-ol,4-Hydroxyquinazoline,4-Quinazolinol,4-Quinazolone,4-Quinazolinone | Antibacterial , Platelet aggregation |
4(3H)-Quinazolinone (4-Hydroxyquinazoline) is a chemically synthesized masonry block, a biologically active nitrogen heterocyclic compound. It possesses various biological properties such as antibacterial, antifungal, an... | |||
T4927 | 4-Guanidinobutanoic acid | 4-GBA,4-Guanidinobutyric acid | Endogenous Metabolite |
4-Guanidinobutanoic acid (4-GBA) is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid transporters hPAT1. | |||
T2S0029 | 4'-Demethylpodophyllotoxin | Others | |
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines. | |||
T5875 | 4-Methoxycinnamic acid | Endogenous Metabolite | |
4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissi. | |||
T8032 | 4-Pentenoic acid | Others , Endogenous Metabolite | |
4-Pentenoic acid, also known as allyl acetic acid or 4-pentenate, belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain. 4-Pentenoic acid is ... | |||
T4858 | 4-Hydroxyphenylpyruvic acid | 4-Hydroxyphenylpyruvic acid | Endogenous Metabolite |
4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydro... | |||
TN2264 | Terpinen-4-ol | Terpinine-4-ol,4-Carvomenthenol | Others , Endogenous Metabolite |
Terpinen-4-ol (4-Carvomenthenol) is a natural product from Pimpinella yunnanensis. | |||
T19137 | 4'-Methylacetophenone | Others | |
4'-Methylacetophenone can be used as a fragrance material. It is wildly occurred in volatile compounds in food and in some natural complex substances. | |||
T7448 | 4-Hydroxyisoleucine | 4-Hydroxy-L-isoleucine | Others |
4-Hydroxyisoleucine (4-Hydroxy-L-isoleucine) has antidepressant-like, antidyslipidemic, and antihyperglycemic effects. It displays an insulinotropic activity. | |||
TN1282 | 4-O-Feruloylquinic acid | Others | |
4-O-Feruloylquinic acid can be useful for the prevention of cardiovascular and other chronic diseases. | |||
Fr16745 | 4-Hydroxybenzyl cyanide | 4-Hydroxyphenylacetonitrile | Endogenous Metabolite |
4-Hydroxybenzyl cyanide (4-Hydroxyphenylacetonitrile) shows strong antioxidative activity. | |||
T4107 | 4-Pyridoxic Acid | Pyridoxic Acid,4-Pyridoxinsaeure | Endogenous Metabolite |
4-Pyridoxic Acid (4-Pyridoxinsaeure), a catabolite of vitamin B6, is a water-soluble B-group vitamin that can be used as a urinary diagnostic biomarker for determining the nutritional status of these vitamins. | |||
T0501 | Mequinol | 4-Hydroxyanisole,Leucobasal,4-Methoxyphenol | Others |
Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosina... | |||
T3734 | 3',4'-Dihydroxyacetophenone | Qingxintong,4-Acetylpyrocatechol | Tyrosinase , Platelet aggregation |
3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity. | |||
T2937 | 4'-Demethylepipodophyllotoxin | 4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin | Microtubule Associated |
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly. | |||
T7443 | 4'-Methoxychalcone | PARP , PPAR | |
4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities. | |||
T10148 | 4-Hydroxynonenal | 4-HNE | Dehydrogenase , Endogenous Metabolite |
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). | |||
T2785 | 4-Methylherniarin | 7-Methoxy-4-methylcoumarin | Others , Antibacterial |
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis. | |||
T8089 | 4-Methyloctanoic acid | 4-Methyl-n-octanoic Acid | Others |
4-Methyloctanoic acid (4-Methyl-n-octanoic Acid) is a natural product. | |||
T8210 | Saikosaponin B4 | Others | |
Saikosaponin B4 is isolated from the MeOH extract of the roots of Bupleurum falcatum L. | |||
TN3209 | 3′,4′,7-Trihydroxyflavone | ATPase , Others , p38 MAPK , NF-κB | |
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto... | |||
T7992 | 4-Hydroxyflavanone | NO Synthase | |
4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects | |||
T13509 | 4-Vinylphenol | Apoptosis , Endogenous Metabolite | |
4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo. | |||
T5S0229 | Isosakuranetin | 4'-Methylnaringenin | Others |
1. Isosakuranetin (4'-Methylnaringenin) has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivity of mice to noxiou... | |||
T2861 | Tyrosol | 4-Hydroxyphenylethanol,2-(4-Hydroxyphenyl)ethanol,4-Hydroxyphenethyl alcohol | Antioxidant , NF-κB , Endogenous Metabolite |
Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives. | |||
T8084 | Dimethyl 4-hydroxyisophthalate | Dimetghyl 4-Hydroxyisophthalate | Others |
Dimethyl 4-hydroxyisophthalate (Dimetghyl 4-Hydroxyisophthalate) is a methyl salicylate analogue, used as a building block in the chemical synthesis. | |||
T36786 | 2-Hydroxy-4-methylbenzaldehyde | Endogenous Metabolite | |
2-Hydroxy-4-methylbenzaldehyde is a human endogenous metabolite. | |||
TN2755 | 2-Desoxy-4-epi-pulchellin | Anti-infection | |
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows sig... | |||
T2A2524 | 2-Hydroxy-4-methoxybenzaldehyde | 4-Methoxysalicylaldehyde | Tyrosinase , Antibacterial |
2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is a chemical compound and an isomer of Vanillin. 2-Hydroxy-4-methoxybenzaldehyde(4-Methoxysalicylaldehyde) could be used to synthesis Urolithin M7. 2-hydroxy-4-... | |||
T7917 | 4'-Hydroxychalcone | 2-Benzal-4-Hydroxyacetophenone | Proteasome |
4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity | |||
TJS0315 | 4-Methyldaphnetin | 7,8-Dihydroxy-4-methylcoumarin,DHMC | Apoptosis , Lipoxygenase |
4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr... | |||
T3325 | Liquiritigenin | 4',7-Dihydroxyflavanone | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Liquiritigenin (4',7-Dihydroxyflavanone), a flavonoid aglycone from licorice, is a highly selective estrogen receptor β (ERβ) agonist. | |||
T0530 | Flavanone | 2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one | Others , Aromatase |
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flavanone hesperidin,... | |||
T19138 | 4-Methylpentanoic acid | Isocaproic Acid | Others |
4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid (SCFA) and a metabolite of 20 alpha-hydroxycholesterol. | |||
T3S1628 | Vitexin-4''-O-glucoside | Vitexin -4''-O-glucoside | Others |
Vitexin-4''-O-glucoside (Vitexin -4''-O-glucoside) could effectively protect ECV-304 cells against cytotoxicity induced by TBHP through resuming mitochondrial function. | |||
T8197 | 2-Methoxy-4-vinylphenol | 2-Methoxy-4-vinylphenol | Others |
2-Methoxy-4-vinylphenol (2-Methoxy-4-vinylphenol) is a natural product. | |||
TJS0338 | 4-Methylesculetin | 4-Methyl-6,7-dihydroxycoumarin,Methylesculetin | Antioxidant , Glutathione Peroxidase |
4-Methylesculetin (Methylesculetin) is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities. | |||
T15686 | L-741626 | 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole | Dopamine Receptor |
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively). | |||
T3752 | 4-Hydroxybenzyl alcohol | 4-Methylolphenol,P-Methylolphenol | Apoptosis , Endogenous Metabolite |
4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybe... | |||
T4759 | Urocanic acid | 4-Imidazoleacrylic acid | Others , Endogenous Metabolite |
Urocanic acid (4-Imidazoleacrylic acid), synthesized in the epidermis, functions as a primary absorber of ultraviolet (UV) radiation in mammalian skin. | |||
------------------------ More ------------------------ |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02731 | SPINK4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPJ-01289 | TIMP-4 Protein, Human, Recombinant (His) | Human | Human Cells |
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreve... | |||
TMPJ-00931 | Serpin A4 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec... | |||
TMPY-03498 | ING4 Protein, Human, Recombinant (His) | Human | E. coli |
ING4 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. ING4 contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling... | |||
TMPY-05786 | SPINK4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPY-01454 | SPINK4 Protein, Human, Recombinant (His) | Human | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPY-00621 | Serpin A1d Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TMPY-00619 | Serpin A1d Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
TMPY-00623 | Serpin A1d Protein, Mouse, Recombinant | Mouse | HEK293 |
TMPJ-01155 | PDCD4 Protein, Human, Recombinant (His) | Human | E. coli |
Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation... | |||
TMPJ-00963 | CDKN2C Protein, Human, Recombinant (His) | Human | E. coli |
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in... | |||
TMPJ-01083 | Serpin E2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea... | |||
TMPY-02425 | Serpin B4, Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin. | |||
TMPY-01216 | XIAP Protein, Human, Recombinant (Avi) | Human | E. coli |
E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, and IAP-like protein, is a protein that belongs to a family of apoptotic suppressor pr... | |||
TMPY-02922 | XIAP Protein, Human, Recombinant (His) | Human | E. coli |
E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, and IAP-like protein, is a protein that belongs to a family of apoptotic suppressor pr... | |||
TMPJ-00279 | Clusterin Protein, Human, Recombinant (His) | Human | Human Cells |
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic bi... | |||
TMPJ-00278 | Clusterin Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic bi... | |||
TMPY-06842 | BMP-4 Protein, Human, Recombinant (E399D) | Human | E. coli |
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP... | |||
TMPJ-00864 | VEGF165 Protein, Human, Recombinant | Human | Human Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator... | |||
TMPY-06074 | B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-05322 | B7-H4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-03524 | B7-H4 Protein, Human, Recombinant (His) | Human | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-01691 | Clusterin Protein, Human, Recombinant (CLU34, His) | Human | HEK293 |
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot... | |||
TMPY-01694 | Clusterin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot... | |||
TMPY-01882 | HE4 Protein, Human, Recombinant (His) | Human | HEK293 |
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP ... | |||
TMPY-04911 | VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated | Human,Cynomolgus | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPK-00823 | VEGF165 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-00749 | FGF-2 Protein, Human, Recombinant | Human | E. coli |
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in... | |||
TMPJ-01320 | BSSP-4 Protein, Human, Recombinant (His) | Human | Human Cells |
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c... | |||
TMPY-00431 | BMP-4 Protein, Mouse, Recombinant (rFc) | Mouse | HEK293 |
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP... | |||
TMPY-02001 | RTN4 Protein, Human, Recombinant (GST) | Human | E. coli |
Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that... | |||
TMPY-00741 | CXCL4 Protein, Human, Recombinant | Human | E. coli |
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w... | |||
TMPJ-00844 | ANXA8 Protein, Human, Recombinant | Human | E. coli |
Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats ... | |||
TMPJ-00840 | ANXA3 Protein, Human, Recombinant | Human | E. coli |
Annexin A3(ANXA3)contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduc... | |||
TMPJ-00101 | TIMP-2 Protein, Human, Recombinant (His) | Human | Human Cells |
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the... | |||
TMPJ-00916 | TIMP-2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP... | |||
TMPY-04471 | APEG1 Protein, Human, Recombinant (His) | Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr... | |||
TMPY-04754 | CASK Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Peripheral plasma membrane protein CASK, also known as calcium/calmodulin-dependent serine protein kinase, CASK and LIN2, is a nucleus, cytoplasm and cell membrane protein which belongs to theMAGUK family. CASK / LIN2... | |||
TMPY-01822 | PTK9 Protein, Human, Recombinant (His & GST) | Human | E. coli |
Twinfilin-1, also known as Protein A6, Protein tyrosine kinase 9, TWF1 and PTK9, is a cytoplasm protein that belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highl... | |||
TMPK-00423 | CD45 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPY-02893 | NT5C3A/NT5C3 Protein, Human, Recombinant | Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot... | |||
TMPK-00822 | VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled | Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-00380 | ANTXR2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneou... | |||
TMPJ-00410 | CD45R0 Protein, Human, Recombinant (His) | Human | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a var... | |||
TMPJ-00782 | Amyloid Precursor Protein, Human, Recombinant (hFc) | Human | Human Cells |
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and... | |||
TMPK-00424 | CD45 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPY-05598 | Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi... | |||
TMPJ-00233 | CD200R1/CRTR2 Protein, Human, Recombinant (His) | Human | Human Cells |
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ... | |||
TMPY-01033 | IL-32 Protein, Human, Recombinant (isoform alpha, His) | Human | HEK293 |
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw... | |||
TMPY-01117 | MRAP Protein, Human, Recombinant (hFc) | Human | HEK293 |
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L1100 | Protease Inhibitor Library | 344 compounds | |
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |