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Home > Cytoskeletal Signaling > Wnt/beta-catenin > ICG001

ICG001

Catalog No. T2237    CAS 847591-62-2    Synonyms: PRI-724, PRI-724 isomer

ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.

Pack Size Availability Price/USD Quantity
2 mg In stock 50.00
5 mg In stock 81.00
10 mg In stock 146.00
25 mg In stock 320.00
50 mg In stock 449.00
100 mg In stock 720.00
1 mL * 10 mM (in DMSO) In stock 146.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.

Receptor:

Wnt/β-catenin;

Chemical Information:
Molecular Weight 548.63
Formula C33H32N4O4
CAS Number 847591-62-2
Solubility

DMSO: 54.9 mg/mL (100 mM)

Ethanol: 27.4 mg/mL (50 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
Reference
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