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Guanfu base H

Catalog No. T11509   CAS 4758-99-0
Synonyms: Atisinium chloride

Guanfu base H is a diterpenoid alkaloid isolated from Aconitum coreanum. It has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 (IC50s: 4 μM and 3.6 μM).

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Guanfu base H Chemical Structure
Guanfu base H, CAS 4758-99-0
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Guanfu base H is a diterpenoid alkaloid isolated from Aconitum coreanum. It has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 (IC50s: 4 μM and 3.6 μM).
Synonyms Atisinium chloride
Molecular Weight 379.96
Formula C22H34ClNO2
CAS No. 4758-99-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. WU Qiong, et al. Simultaneous Determination of Guanfu Base A,Guanfu Base I and Guanfu Base H in Radix Aconitum coreanum(Lévl) Rapaics by RP-HPLC. Progress in Pharmaceutical Sciences. 2011, 35(5), 230-233. 2. Wangchuk P, et al. Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum. J Ethnopharmacol. 2010 Aug 9;130(3):559-62.

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Keywords

Guanfu base H 4758-99-0 Others Atisinium Chloride Atisinium chloride inhibitor inhibit

 

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