Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | GF 15 is a potent inhibitor of centrosomal clustering in tumor cells. |
In vitro | GF 15 exhibits potent cytotoxicity in a concentration-dependent manner against a broad spectrum of tumor cell types including colon, cervix, glioblastoma, pancreas, leukemia, and myeloma-derived cell lines with IC50s of 1-5 μM.GF 15 leads to multipolar mitosis induction with an EC50 of 900 nM. |
In vivo | Treatment of mouse xenograft models of human colon cancer and multiple myeloma with GF 15 results in tumor growth inhibition and significantly prolonged survival. |
Molecular Weight | 428.86 |
Formula | C23H21ClO6 |
CAS No. | 888042-13-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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GF 15 888042-13-5 Others GF15 GF-15 inhibitor inhibit