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Furagin

Catalog No. T4273 CAS 1672-88-4

Synonyms: F-35, Akritoin, Furazidine, NF-416, Furazidin

Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.

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Furagin, CAS 1672-88-4

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 29.00
1 mL * 10 mM (in DMSO)	In stock	$ 43.00

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Purity: 100%

Biological Description

Chemical Properties

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Description	Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.
In vitro	The furagin concentrations in serum remain several hours above the MIC concentrations of many pathogenic bacteria. Despite the high concentrations in serum, the urine levels of furagin were generally lower than those of nitrofurantoin. The 24 hr recoveries in urine were 8--13% for furagin and about 36% for nitrofurantoin.
In vivo	A time-independent increase in SCE frequency was found in lymphocytes of children treated with furagin. Total CA frequency did not differ significantly between groups of children with various duration of furagin treatment.

Synonyms	F-35, Akritoin, Furazidine, NF-416, Furazidin
Molecular Weight	264.19
Formula	C10H8N4O5
CAS No.	1672-88-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 33 mg/mL

References and Literature

1. Mannisto P, et al. Pharmacokinetics of furagin, a new nitrofurantoin congener, on human volunteers. Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):264-70. 2. Slapsyte G, et al. Cytogenetic analysis of children under long-term antibacterial therapy with nitroheterocyclic compound furagin. Mutat Res. 2001 Apr 5;491(1-2):25-30. 3. Dybowski B, et al. Ciprofloxacin and furagin in acute cystitis: comparison of early immune and microbiological results. Int J Antimicrob Agents. 2008 Feb;31(2):130-4.

Related compound libraries

This product is contained In the following compound libraries：

Drug-induced Liver Injury (DILI) Compound Library NO PAINS Compound Library Covalent Inhibitor Library Anti-Infection Compound Library Antibiotics Library Human Metabolite Library Bioactive Compound Library Immunology/Inflammation Compound Library Anti-Bacterial Compound Library Bioactive Compounds Library Max

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Furagin 1672-88-4 Microbiology/Virology Antibacterial F-35 Akritoin Bacterial Furazidine F 35 inhibit Inhibitor NF 416 NF416 NF-416 Furazidin F35 inhibitor

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