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Formestane

Catalog No. T1099 CAS 566-48-3

Synonyms: CGP-32349, NSC 282175

Formestane is a selective aromatase inhibitor(IC50=80 nM) with antineoplastic activity.

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Formestane, CAS 566-48-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Formestane is a selective aromatase inhibitor(IC50=80 nM) with antineoplastic activity.
Targets&IC50	Aromatase:80 nM

Synonyms	CGP-32349, NSC 282175
Molecular Weight	302.414
Formula	C19H26O3
CAS No.	566-48-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 57 mg/mL (188.5 mM)

H2O: <1 mg/mL

Ethanol: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Wiseman LR, Goa KL. Drugs Aging. 1996 Oct;9(4):292-306.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Endocrinology-Hormone Compound Library Inhibitor Library Drug-induced Liver Injury (DILI) Compound Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Active Compound Library Anti-Breast Cancer Compound Library Toxic Compound Library Approved Drug Library

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Related compounds with same targets

Eriodictyol chalcone Fadrozole hydrochloride Fadrozole Oleuropein Endoxifen Calceolarioside B Obacunone alpha-Naphthoflavone

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Formestane 566-48-3 Endocrinology/Hormones Aromatase CGP-32349 NSC 282175 Inhibitor inhibitor inhibit

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