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Fedratinib

Catalog No. T1995    CAS 936091-26-8    Synonyms: SAR 302503, TG-101348

Fedratinib (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.

Pack Size Availability Price/USD Quantity
2 mg In stock 50.00
5 mg In stock 71.00
10 mg In stock 110.00
25 mg In stock 219.00
50 mg In stock 320.00
100 mg In stock 480.00
1 mL * 10 mM (in DMSO) In stock 80.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Fedratinib (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.

Receptor:

FLT3; JAK2; JAK2 (V617F); RET;

Chemical Information:
Molecular Weight 524.68
Formula C27H36N6O3S
CAS Number 936091-26-8
Solubility

DMSO: 93 mg/mL (177.3 mM)

Ethanol: <1 mg/mL

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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