Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 105.00 | |
10 mg | In stock | $ 176.00 | |
25 mg | In stock | $ 359.00 | |
50 mg | In stock | $ 578.00 | |
100 mg | In stock | $ 828.00 |
Description | FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively. |
Targets&IC50 | COX-2:65 µM, COX-1:28 nM |
Synonyms | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride, 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride |
Molecular Weight | 459.99 |
Formula | C23H26ClN3O3S |
CAS No. | 130717-51-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4 mg/mL(8.70 mM)
H2O: 2 mg/mL(4.35 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
FR 122047 130717-51-0 Immunology/Inflammation Neuroscience COX FR 122047 hydrochloride Cyclooxygenase FR-122047 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride FR122047 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride inhibit Inhibitor inhibitor