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EHP-101

Catalog No. T13289 CAS 1818428-24-8

Synonyms: VCE-004.8

EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents diet-induced obesity.

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EHP-101, CAS 1818428-24-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 109.00
5 mg	In stock	$ 239.00
10 mg	In stock	$ 397.00
25 mg	In stock	$ 652.00
50 mg	In stock	$ 913.00
100 mg	In stock	$ 1,230.00
1 mL * 10 mM (in DMSO)	In stock	$ 263.00

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Purity: 99.22%

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Description	EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents diet-induced obesity.
In vivo	In HFD mice, VCE-004.8 (injection; 20?mg/kg/day; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume, and plasma triglycerides levels. VCE-004.8 can also significantly improve glucose tolerance, reduce leptin levels (a sign of obesity) and increase the levels of adiponectin and glucagon (GLP-1 and GIP) [1].

Synonyms	VCE-004.8
Molecular Weight	433.58
Formula	C28H35NO3
CAS No.	1818428-24-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 49 mg/mL (113.01 mM)

References and Literature

1. Navarrete C, et al. Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy. J Neuroinflammation. 2018 Mar 1;15(1):64. 2. Palomares B, et al. VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity. Sci Rep. 2018 Oct 31;8(1):16092.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library GPCR Compound Library Drug Repurposing Compound Library Nuclear Receptor Compound Library Orally Active Compound Library Glycolysis Compound Library HIF-1 Signaling Pathway Compound Library Anti-Diabetic Compound Library Neuronal Signaling Compound Library

Related Products

Related compounds with same targets

CB2R/FAAH modulator-1 SCH-336 ML-193 AM1241 CB2R agonist 3 MJ 15 RVD-Hpα acetate(1193362-76-3 free base) CB1R antagonist 1

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

EHP-101 1818428-24-8 Chromatin/Epigenetic DNA Damage/DNA Repair GPCR/G Protein Metabolism PPAR Cannabinoid Receptor HIF/HIF Prolyl-Hydroxylase Peroxisome proliferator-activated receptors VCE-004.8 EHP101 HIF-PH Hypoxia-inducible factors inhibit VCE-?004.8 Inhibitor HIFs EHP 101 VCE-004.8 inhibitor

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