Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 132.00 | |
5 mg | In stock | $ 328.00 | |
10 mg | In stock | $ 528.00 | |
25 mg | In stock | $ 859.00 | |
50 mg | In stock | $ 1,190.00 | |
100 mg | In stock | $ 1,580.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 363.00 |
Description | EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity. |
Targets&IC50 | EGFRL858R/T790M:28 nM, EGFR(WT):7 nM |
In vitro | EGFR-IN-9 shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM[1]. |
Molecular Weight | 476.53 |
Formula | C29H24N4O3 |
CAS No. | 1226549-39-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90mg/mL (188.9mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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EGFR-IN-9 1226549-39-8 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR EGFRIN9 EGFR IN 9 inhibitor inhibit