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Dovitinib Dilactic Acid

Catalog No. T6193    CAS 852433-84-2    Synonyms: Dovitinib (TKI-258) Dilactic Acid, TKI258 Dilactic acid

Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

Pack Size Availability Price/USD Quantity
2 mg Inquiry 50.00
5 mg Inquiry 84.00
10 mg Inquiry 127.00
25 mg Inquiry 260.00
50 mg Inquiry 450.00
100 mg Inquiry 720.00
1 mL * 10 mM (in DMSO) Inquiry 183.00
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Biological Activity:

Product Description:

Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

Receptor:

c-Kit; FGFR1; FGFR3; FLT3; VEGFR3/FLT4;

Chemical Information:
Molecular Weight 572.59
Formula C21H21FN6O·2C3H6O3
CAS Number 852433-84-2
Solubility

DMSO: 83 mg/mL (145 mM)

Ethanol: <1 mg/mL

Water: 64 mg/mL (111.8 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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