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Metabolism Vitamin Dexpanthenol

Dexpanthenol

Catalog No. T1437   CAS 81-13-0
Synonyms: D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol

Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

Dexpanthenol, CAS 81-13-0
Pack Size Availability Price/USD Quantity
25 mg In stock 20.00
50 mg In stock 26.00
100 mg In stock 33.00
200 mg In stock 42.00
500 mg In stock 50.00
1 g In stock 59.00
1 mL * 10 mM (in DMSO) In stock 54.00
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Purity 99.74%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.
Targets&IC50 VB5
In vivo Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2].
Synonyms D-Panthenol , Pantothenol , Ilopan , D-Pantothenyl alcohol
Purity 99.74%
Molecular Weight 205.25
Formula C9H19NO4
CAS No. 81-13-0

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 33 mg/mL (160.78 mM), Need ultrasonic and warming

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Zakaria MM, et al. J Pak Med Assoc. 2011, 61(9):889-92. 2. Heise R, et al. Skin Pharmacol Physiol. 2012, 25(5):241-8.

Related compound libraries

This product is contained In the following compound libraries:
Approved Drug Library Bioactive Compound Library Inhibitor Library Natural Compound Library for HTS Anti-cancer Compound Library Clinical Compound Library Human Endogenous Metabolite Compound Library FDA-approved Drug Library Immunology/Inflammation Compound Library Anti-cancer Approved drug Library Anti-cancer Clinical Compound Library Anti-Metabolism Disease Compound Library Anti-obesity Compound Library Antitumor Natural Products Library Anti-cancer Drug library Drug Repurposing Library Target-Focused Phenotypic Screening Library NMPA-Approved Drug Library FDA Approved & Pharmacopeial Drug Library Gut Microbial Metabolite Library

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