Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Desfluoro-ezetimibe is the defluorinated impurity of ezetimibe. Ezetimibe is an effective, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor and an effective Nrf2 activator.
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Description | Desfluoro-ezetimibe is the defluorinated impurity of ezetimibe. Ezetimibe is an effective, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor and an effective Nrf2 activator. |
In vitro | In Ezetimibe's synthesis process development research, the impurity content detected in the final product using reversed-phase gradient high performance liquid chromatography (HPLC) method was 0.05% to 0.15%, and its molecular weight was determined by LC-MS analysis. The impurity is defluorized ezetimibe. |
Molecular Weight | 391.43 |
Formula | C24H22FNO3 |
CAS No. | 302781-98-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Desfluoro-ezetimibe 302781-98-2 Others Desfluoro ezetimibe Desfluoroezetimibe inhibitor inhibit