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Coumarin-3-carboxylic acid

Catalog No. TJS0339   CAS 531-81-7
Synonyms: 3-Carboxycoumarin

The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways; this combination may have a wide therapeutic and/or adjuvant therapeutic application in the treatment of lung cancer.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Coumarin-3-carboxylic acid Chemical Structure
Coumarin-3-carboxylic acid, CAS 531-81-7
Pack Size Availability Price/USD Quantity
500 mg In stock $ 48.00
1 mL * 10 mM (in DMSO) In stock $ 29.00
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Purity: 99.76%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways; this combination may have a wide therapeutic and/or adjuvant therapeutic application in the treatment of lung cancer.
Synonyms 3-Carboxycoumarin
Molecular Weight 190.15
Formula C10H6O4
CAS No. 531-81-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 199.8 mM

TargetMolReferences and Literature

1. Xin Liu, et al. Enhanced suppression of proliferation and migration in highly-metastatic lung cancer cells by combination of valproic acid and coumarin-3-carboxylic acid and its molecular mechanisms of action. Cytotechnology. 2013 Aug; 65(4): 597–608.

Related compound libraries

This product is contained In the following compound libraries:
Tyrosine Kinase Inhibitor Library Anti-Cancer Active Compound Library Anti-Ovarian Cancer Compound Library HIF-1 Signaling Pathway Compound Library Anti-Tumor Natural Product Library Anti-Cardiovascular Disease Compound Library Natural Product Library Anti-Cancer Compound Library Anti-Pancreatic Cancer Compound Library Bioactive Compound Library

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Keywords

Coumarin-3-carboxylic acid 531-81-7 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Coumarin 3 carboxylic acid Inhibitor 3-Carboxycoumarin inhibit Coumarin3carboxylic acid inhibitor

 

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