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Ceftriaxone sodium salt

Catalog No. T10754   CAS 74578-69-1
Synonyms: Disodium ceftriaxone

Ceftriaxone sodium salt is an antibiotic useful for the treatment of a number of bacterial infections.

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Ceftriaxone sodium salt Chemical Structure
Ceftriaxone sodium salt, CAS 74578-69-1
Pack Size Availability Price/USD Quantity
50 mg 5 days $ 33.00
100 mg 5 days $ 47.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ceftriaxone sodium salt is an antibiotic useful for the treatment of a number of bacterial infections.
In vitro Ceftriaxone inhibits bacterial cell wall synthesis by means of binding to the penicillin-binding proteins (PBPs). Inhibition of PBPs would in turn inhibit the transpeptidation step in peptidoglycan synthesis which is required for bacterial cell walls. Like other cephalosporins, ceftriaxone is bacteriocidal and exhibits time-dependent killing. Ceftriaxone is a stimulator of EAAT2 expression with neuroprotective effects in both in vitro and in vivo models based in part on its ability to inhibit neuronal cell death by glutamate excitotoxicity.
Synonyms Disodium ceftriaxone
Molecular Weight 577.56
Formula C18H18N8NaO7S3
CAS No. 74578-69-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 40 mg/mL (66.60 mM)

DMSO: 50 mg/mL (83.26 mM), sonification is recommended.

TargetMolReferences and Literature

1. Lee, S.G., et al., Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes. J Biol Chem, 2008. 283(19): p. 13116-23.

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Keywords

Ceftriaxone sodium salt 74578-69-1 Others Disodium ceftriaxone Ceftriaxone sodium inhibitor inhibit

 

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