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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6458 | CYC-116 | FLT , VEGFR , S6 Kinase , CDK , Aurora Kinase | |
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 ... |