Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK.
Description | CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK. |
In vitro | CMK inhibits the growth of Cdc5 (L158G) with IC50 of 36 nM, greater than 30 μM for wild type Cdc5. CMK exhibits a concentration-dependent first cell cycle mitotic arrest in the cdc5-as1 strain (IC50: 1.1 μM). CMK inhibition of Cdc5 (L158G) leads to a first cell cycle anaphase arrest and delay in anaphase spindle migration. |
Molecular Weight | 358.82 |
Formula | C18H19ClN4O2 |
CAS No. | 821794-90-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (418.04 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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CMK 821794-90-5 Others inhibitor inhibit