Search Result

Search Results for " 6-in-2 "

Targets

VEGFR

334

Compounds

Natural Products

459

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T37078	VEGFR-2-IN-6		VEGFR
	VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].		VEGFR
T10736	CDK4/6-IN-2		CDK
	CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor (IC50s: 2.7 and 16 nM).		CDK
T39640	JAB-3068	SHP2-IN-6	Phosphatase
	JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor with anticancer and antitumor activity for the study of breast, lung, and esophageal cancers.		Phosphatase
T40443	JAK2-IN-6	JAK2-IN-6	JAK
	JAK2-IN-6, a polysubstituted aminothiazole derivative, is a potent and selective inhibitor of JAK2 (ic50 at 22.86 μg/mL). Jak2-in-6 inhibits the activity of JAK2 enzymes by interfering with Jak2-related signaling pathway...		JAK
T11374	GCN2-IN-6		Others , PERK
	GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6 is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8...		Others , PERK
T9017	HPK1-IN-2	Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2	Others , FLT , Src
	HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1; IC50<0.05 μΜ). It also...		Others , FLT , Src
T9215	ELOVL6-IN-2		Others
	ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.		Others
T19206	β-Lactamase-IN-1	4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1	Antibacterial
	β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.		Antibacterial
T9943	Firefly luciferase-IN-1		Others
	Firefly luciferase-IN-1 is a 2-benzylidene tetrahydronaphthone derivative and can be used as a firefly luciferase inhibitor in kit.		Others
T14918	CDK9-IN-2		Others , CDK
	CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively.		Others , CDK
T8917	PAR-2-IN-1	IUN76750	Protease-activated Receptor
	PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.		Protease-activated Receptor
T62061	COX-2-IN-6		COX , Prostaglandin Receptor
	COX-2-IN-6 is a potent, selective, and orally available cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.84 μM and a Ki of 69 nM.COX-2-IN-6 inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM.COX-2-IN-6 is u...		COX , Prostaglandin Receptor
T15268	FAAH-IN-2	O-Desmorpholinopropyl Gefitinib	FAAH , Autophagy
	FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).		FAAH , Autophagy
T2246	LRRK2-IN-1		Apoptosis , LRRK2 , CDK
	LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.		Apoptosis , LRRK2 , CDK
T40323	EZH2-IN-6	EZH2-IN-6
	EZH2-IN-6 is an EZH2 inhibitor with enhanced antitumor activity.
T39641	SHP2-IN-6 hydrochloride	SHP2-IN-6 hydrochloride
	SHP2-IN-6 hydrochloride is a highly potent inhibitor of SHP2 with an IC50 of 25.8 nM.
T74003	HDAC3/6-IN-2
	HDAC3/6-IN-2 (compound 15) is a dual inhibitor targeting HDAC6 and HDAC3, exhibiting potent activity with IC50 values of 0.368 μM for HDAC6 and 0.635 μM for HDAC3. This compound demonstrates antitumor effects by inducing...
T62686	MNK1/2-IN-6
	MNK1/2-IN-6 is a potent and selective inhibitor of MNK1 (IC50: 2.3 nM), MNK2 (IC50: 3.4 nM), and MNK1/2-IN-6 induces apoptosis in a concentration-dependent manner.
T63676	Bcl-2-IN-6
	Bcl-2-IN-6 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2) that downregulates Bcl-2 expression and increases the expression of p53, Bax, and caspase-7 mRNA. bcl-2-IN-7 induces cell cycle arrest and apoptosis in breast...
T79054	TRPC3/6-IN-2
	TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].
T60785	SARS-CoV-2-IN-6
	SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.
T22256	C-Kit-IN-5-1	3-(2-Aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl)pyridin-2(1H)-one,AMG-25,3-(2-aminoquinazolin-6-yl)-4-methyl-1-[4-(1,3-oxazol-2-yl)phenyl]pyridin-2-one	c-Kit
	c-Kit-IN-5-1 (AMG-25) is a novel selective and potent c-Kit inhibitor.		c-Kit
T62248	SARS-CoV-2 nsp13-IN-6
	SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on ssDNA+ATPase (IC50: 27 μM) and ssDNA-ATPase (IC50: 33 μM). nsp13-IN-6 can be used in anti-COVID-19 st...
T72451	SARS-CoV-2 Mpro-IN-6
	SARS-CoV-2 Mpro-IN-6 is a selective, covalent, and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an inhibition concentration (IC50) of 0.18 μM. It does not inhibit human cathepsins B, F, K, and L ...
T72370	SARS-CoV-2 3CLpro-IN-6
	SARS-CoV-2 3CLpro-IN-6 is a reversible covalent inhibitor targeting the SARS-CoV-2 3CL protease, demonstrating potent inhibitory activity with an IC50 of 4.9 μM. It is utilized in the research of coronavirus disease 2019...
T0663	2-Bromo-6-methoxynaphthalene		5-HT Receptor
	2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.		5-HT Receptor
T9347	EAAT2 activator 1	3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine	transporter
	EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.		transporter
T61556	GRK6-IN-2		GRK
	GRK6-IN-2 is a potent G protein-coupled receptor kinase 6 (GRK6) inhibitor with potential antitumor activity.GRK6-IN-2 has been studied in multiple myeloma.		GRK
T3089	6-Thioguanine	6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine	Apoptosis , DNA Methyltransferase , SARS-CoV , Endogenous Metabolite , DUB , Autophagy
	6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
T67874	PFKFB3-IN-2		Glucokinase
	PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. Anti-sense treatment against PFKFB3 was shown to reduce tumor growth rate in vivo.		Glucokinase
T3504	AZD5153 6-Hydroxy-2-naphthoic acid	AZD5153,AZD-5153 HNT salt	Epigenetic Reader Domain
	AZD5153 6-Hydroxy-2-naphthoic acid (AZD5153) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatments.		Epigenetic Reader Domain
T0637	2-Acetyl-6-methoxynaphthalene		Others
	2-Acetyl-6-methoxynaphthalene, the key intermediate of naphthalene tome and naproxen, is used in synthetic non-steroidal anti-inflammatory analgesic medicine and.		Others
T2172	SQ22536	9-(tetrahydrofuran-2-yl)-9h-purin-6-amine,SQ 22536	AChR
	SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membrane preparations from catfish (Ictalurus melas) and rat isola...		AChR
T39988	6'-GNTI dihydrochloride		Opioid Receptor , Akt
	6'-GNTI dihydrochloride is a κ-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of β-aspirin 2. 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neur...		Opioid Receptor , Akt
T9462	2-Amino-6-cyclopropylamino-9H-purine		Others
	2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-t...		Others
T2294	BG45		Apoptosis , HDAC
	BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.		Apoptosis , HDAC
T17326	2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide	2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide	Others , PROTAC Linker
	2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide (2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide) is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.		Others , PROTAC Linker
T14188	ALLO-2		Hedgehog/Smoothened , Smo
	ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.		Hedgehog/Smoothened , Smo
T9095	Necrostatin-34	2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4	RIP kinase
	Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.		RIP kinase
T5509	FPTQ		GluR
	FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1]. In addition to its robust inhibitory properties, FPTQ exhibits notable antioxidant ...		GluR
T15433	GSK2795039		Apoptosis , Reactive Oxygen Species , ROS , NADPH
	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).		Apoptosis , Reactive Oxygen Species , ROS , NADPH
T16436	PBOX 6	PBOX-6	Apoptosis
	PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits breast cancer cell growth in vitro and selectively induces apoptosis in leukemia cells via c-Jun NH2 terminal kin...		Apoptosis
T26086L	1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one		Others
	1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one is an isomer of Rilmakalim, a potassium channel opener (PCO), which can activate ATP-sensitive K+ channels in the heart or other tissues		Others
T16315	NH2-PEG6-Boc		PROTAC Linker
	NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1]. NH2-PEG6-Boc is also a non-cleavable 6-unit PEG ADC linker used in antibody-drug conjugates(ADCs) synthesis[2].		PROTAC Linker
T8749	CS-B1628	tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate,ACN-053859	Others
	CS-B1628 (tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate) can be used in the synthesis of pyrimidine derivatives, with the potential use of being a starting materi...		Others
T36310	AKT-IN-6	INCB-047775	Akt
	AKT-IN-6 (INCB-047775) has an inhibitory effect on ATK. Akt is an important component of cellular signaling for growth factors, cytokines, and other cell stimuli. Abnormal Akt activation has been associated with the deve...		Akt
T64393	6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile		Others
	6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilize...		Others
T17243	VU0463271	N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide	Potassium Channel
	VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM ...		Potassium Channel
T3175	LDHA-IN-4	AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase
	LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 μM.		Dehydrogenase
T3502	C29		TLR
	C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.		TLR

Compounds

Synonym: Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2

Target: Others, FLT, Src

Synonym: 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1

Target: Antibacterial

Firefly luciferase-IN-1

Target: Protease-activated Receptor

COX-2-IN-6

T62061

Synonym:

Target: COX, Prostaglandin Receptor

FAAH-IN-2

T15268

Synonym: O-Desmorpholinopropyl Gefitinib

Target: FAAH, Autophagy

LRRK2-IN-1

T2246

Synonym:

Target: Apoptosis, LRRK2, CDK

SHP2-IN-6 hydrochloride

T39641

Synonym: SHP2-IN-6 hydrochloride

Synonym: 3-(2-Aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl)pyridin-2(1H)-one,AMG-25,3-(2-aminoquinazolin-6-yl)-4-methyl-1-[4-(1,3-oxazol-2-yl)phenyl]pyridin-2-one

Target: c-Kit

SARS-CoV-2 nsp13-IN-6

SARS-CoV-2 3CLpro-IN-6

T72370

Synonym:

Target:

2-Bromo-6-methoxynaphthalene

T0663

Synonym:

Target: 5-HT Receptor

EAAT2 activator 1

T9347

Synonym: 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine

Synonym: 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine

Target: Apoptosis, DNA Methyltransferase, SARS-CoV, Endogenous Metabolite, DUB, Autophagy

AZD5153 6-Hydroxy-2-naphthoic acid

T3504

Synonym: AZD5153,AZD-5153 HNT salt

Target: Epigenetic Reader Domain

2-Acetyl-6-methoxynaphthalene

Synonym: 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine,SQ 22536

Target: AChR

6'-GNTI dihydrochloride

T39988

Synonym:

Target: Opioid Receptor, Akt

2-Amino-6-cyclopropylamino-9H-purine

Target: Apoptosis, HDAC

2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide

T17326

Synonym: 2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide

Target: Others, PROTAC Linker

ALLO-2

T14188

Synonym:

Target: Hedgehog/Smoothened, Smo

Necrostatin-34

T9095

Synonym: 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4

Target: Apoptosis, Reactive Oxygen Species, ROS, NADPH

1-((3R,4S)-3-hydroxy-2,2-dimethyl-6-(phenylsulfonyl)chroman-4-yl)pyrrolidin-2-one

Target: PROTAC Linker

CS-B1628

T8749

Synonym: tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate,ACN-053859

6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile

Synonym: N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide

Target: Potassium Channel

LDHA-IN-4

T3175

Synonym: AZ 33,AZ-33,LDHA Inhibitor,AZ33

Target: Dehydrogenase

Cat No.	Product Name	Synonyms	Targets
TN7198	6-Bromoindole-3-acetonitrile	6-Bromo-1H-indole-3-acetonitrile,ZINC13379652,2-(6-bromo-1H-indol-3-yl)acetonitrile	Others
	6-Bromoindole-3-acetonitrile (2-(6-bromo-1H-indol-3-yl)acetonitrile) is a marine derived natural products found in Pseudosuberites hyalinus.		Others
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside		Others
	Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside		Others
	Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TN3176L	(2R)-6-Methoxynaringenin
	(2R)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one is one of the potentially active components in Scutellaria baicalensis.
T4406	2,6-Dimethylbenzoquinone	m-Xyloquinone,2,6-Dimethylquinone	Others
	2,6-Dimethylbenzoquinone (2,6-Dimethylquinone) is a benzoquinone, a chemical compound found in Rauvolfia vomitoria and in Tibouchina pulchra.At physiological concentrations 2, 6-Dimethoxy-p-benzoquinone is an antibacteri...		Others
T27012	Chrysotoxine	Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-,4-[2-(3,4-Dimethoxyphenyl)ethyl]-2,6-dimethoxyphenol	NF-κB
	Chrysotoxine (Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-) inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via NF-κB modulation and mitochondria protection.		NF-κB
T6S1699	Shogaol	[6]-Shogaol,6-Shogaol	Lipoxygenase , Autophagy
	1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...		Lipoxygenase , Autophagy
TN1308	6-Hydroxyflavanone		Others , Lipoxygenase , COX , GABA Receptor
	6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), as well as opioid and GABA-A r...		Others , Lipoxygenase , COX , GABA Receptor
TN2719	2',4'-Dihydroxy-6'-methoxyacetophenone		Antibacterial
	2',4'-Dihydroxy-6'-methoxyacetophenone is a phenolic acetophenone extracted from Leguminosae and Asteraceae with antimicrobial activity and can be used in the synthesis of pyran-sickle.		Antibacterial
T6S1371	Isovitexin	Homovitexin,Saponaretin,Apigenin-6-C-Glucoside	NF-κB , JNK , Glucosidase
	1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.		NF-κB , JNK , Glucosidase
T4873	2-Amino-1-phenylethanol		Endogenous Metabolite
	2-Hydroxyphenethylamine has been found in human testicle tissue, and has also been primarily detected in blood. 2-Hydroxyphenethylamine can be converted into 2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]ami...		Endogenous Metabolite
T3S1967	(S)-Indoximod	N-ME-Tryptophan,Abrine,L-Abrine	Others , Indoleamine 2,3-Dioxygenase (IDO)
	(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...		Others , Indoleamine 2,3-Dioxygenase (IDO)
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
T4832	Cytosine	6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine	Endogenous Metabolite
	Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le...		Endogenous Metabolite
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T5S2357	Acetylcorynoline	(+)-Corynoline Acetate,O-Acetylcorynoline	Antifungal
	1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3...		Antifungal
T6S0234	Toosendanin		Others
	1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin i...		Others
T6S1683	Demethoxycurcumin	Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin	Apoptosis , Antioxidant , Antibacterial , Autophagy
	1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...		Apoptosis , Antioxidant , Antibacterial , Autophagy
T2928	α-L-Rhamnose monohydrate	L-Rhamnose monohydrate,6-deoxy-L-mannose monohydrate	Others
	α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate) is a component of bacterial polysaccharides where it plays an important role in pathogenicity.		Others
T2940	6-Hydroxyflavone	6-HF	GABA Receptor
	6-Hydroxyflavone (6-HF) is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydro...		GABA Receptor
T6S0033	Crotonoside	Isoguanosine,2-HYDROXYADENOSINE	Others , FLT , HDAC
	1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stim...		Others , FLT , HDAC
T3S0057	Dihydrochelerythrine	12,13-Dihydrochelerythrine	Antifungal
	1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ...		Antifungal
T7113	Paradol	6-paradol,[6]-Gingerone	COX
	Paradol ([6]-Gingerone) is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activit...		COX
T4S0145	Corylifol A	Corylinin	hCE , STAT , UGT
	1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...		hCE , STAT , UGT
T5S1805	5,7-Dihydroxychromone	5,7-Dihydroxy-4H-Chromen-4-One	Others , Virus Protease , PARP , Caspase , Nrf2
	1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...		Others , Virus Protease , PARP , Caspase , Nrf2
T5S1889	Yunaconitine	Guayewuanine B	Others
	1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows po...		Others
T4S1422	Praeruptorin E		Others , Calcium Channel
	1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activit...		Others , Calcium Channel
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T5S1172	Tiliroside	Tribuloside	Antioxidant
	1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati...		Antioxidant
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T4S1962	Beta-Asarone	Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin	NF-κB , JNK
	1. beta-Asarone (Cis-Isoelemicin) may be a potential preventive drug for Alzheimer's disease. 2. Beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. 3. The co-administration of be...		NF-κB , JNK
T6S1684	8-Gingerol		Antioxidant , Antibacterial , TRP/TRPV Channel
	1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...		Antioxidant , Antibacterial , TRP/TRPV Channel
T6S1141	Ganoderic acid A		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
	1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a...		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
T2S1865	Octyl gallate	Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8	Antioxidant , Influenza Virus , Reactive Oxygen Species , Antibacterial , Antifungal , HSV
	1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, ...
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T5S1285	(+)-(3R,8S)-Falcarindiol	Falcarindiol	Others
	1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a nov...		Others
T5S2343	Acetylshikonin	Acetyl shikonin	Others , P450 , AChE
	1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...		Others , P450 , AChE
T2S2215	Crebanine		Apoptosis , Others , Akt
	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat...		Apoptosis , Others , Akt
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T3S2259	Methyl eugenol	4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether	GABA Receptor
	1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its...		GABA Receptor
T4115	Auraptene	7-geranyloxycoumarin	MMP , BACE
	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...		MMP , BACE
T4S1551	Cinnamaldehyde	Cinnamic Aldehyde	HIF
	1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...		HIF
T14062	6"-O-Acetylgenistin		Others
	6-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 10.6 μM[1][2].		Others
TN6057	1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone	(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one
	(Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one shows strong inhibitory activity on leukotriene biosynthesis in human polymorphonuclear granulocytes, and it is very effective against mycobacteria.
TN5033	Skullcapflavone I		IL Receptor , Caspase , Prostaglandin Receptor
	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep...		IL Receptor , Caspase , Prostaglandin Receptor
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Natural Products

6-Bromoindole-3-acetonitrile

TN7198

Synonym: 6-Bromo-1H-indole-3-acetonitrile,ZINC13379652,2-(6-bromo-1H-indol-3-yl)acetonitrile

Target: Others

Chrysin 6-C-arabinoside 8-C-glucoside

TN1487

Synonym:

Target: Others

Chrysin 6-C-glucoside 8-C-arabinoside

TN1488

Synonym:

Target: Others

(2R)-6-Methoxynaringenin

TN3176L

Synonym:

Target:

2,6-Dimethylbenzoquinone

T4406

Synonym: m-Xyloquinone,2,6-Dimethylquinone

Target: Others

Chrysotoxine

T27012

Synonym: Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-,4-[2-(3,4-Dimethoxyphenyl)ethyl]-2,6-dimethoxyphenol

Target: NF-κB

Shogaol

T6S1699

Synonym: [6]-Shogaol,6-Shogaol

Target: Lipoxygenase, Autophagy

6-Hydroxyflavanone

TN1308

Synonym:

Target: Others, Lipoxygenase, COX, GABA Receptor

2',4'-Dihydroxy-6'-methoxyacetophenone

TN2719

Synonym:

Target: Antibacterial

Isovitexin

T6S1371

Synonym: Homovitexin,Saponaretin,Apigenin-6-C-Glucoside

Target: NF-κB, JNK, Glucosidase

2-Amino-1-phenylethanol

T4873

Synonym:

Target: Endogenous Metabolite

(S)-Indoximod

T3S1967

Synonym: N-ME-Tryptophan,Abrine,L-Abrine

Target: Others, Indoleamine 2,3-Dioxygenase (IDO)

Pentagalloylglucose

T3794

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose

Target: Influenza Virus

Cytosine

T4832

Synonym: 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine

Target: Endogenous Metabolite

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Acetylcorynoline

T5S2357

Synonym: (+)-Corynoline Acetate,O-Acetylcorynoline

Synonym: Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

α-L-Rhamnose monohydrate

T2928

Synonym: L-Rhamnose monohydrate,6-deoxy-L-mannose monohydrate

Target: GABA Receptor

Crotonoside

T6S0033

Synonym: Isoguanosine,2-HYDROXYADENOSINE

Target: Others, FLT, HDAC

Dihydrochelerythrine

T3S0057

Synonym: 12,13-Dihydrochelerythrine

Target: Antifungal

Paradol

T7113

Synonym: 6-paradol,[6]-Gingerone

Target: hCE, STAT, UGT

5,7-Dihydroxychromone

T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Yunaconitine

T5S1889

Synonym: Guayewuanine B

Target: Others, Calcium Channel

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Tetrahydrocoptisine

T4S2063

Synonym: STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

beta-Asarone

T4S1962

Synonym: Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin

Target: Antioxidant, Antibacterial, TRP/TRPV Channel

Ganoderic acid A

T6S1141

Synonym:

Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy

Octyl gallate

T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

Linalool

T2S2264

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

(+)-(3R,8S)-Falcarindiol

T5S1285

Synonym: Falcarindiol

Target: Others

Acetylshikonin

T5S2343

Synonym: Acetyl shikonin

Target: Others, P450, AChE

Crebanine

T2S2215

Synonym:

Target: Apoptosis, Others, Akt

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Triamcinolone

T0798

Synonym: Fluoxyprednisolone,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Methyl eugenol

T3S2259

Synonym: 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether

Target: GABA Receptor

Auraptene

T4115

Synonym: 7-geranyloxycoumarin

Target: MMP, BACE

Cinnamaldehyde

T4S1551

Synonym: Cinnamic Aldehyde

1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone

TN6057

Synonym: (Z)-1-Methyl-2-(undec-6-enyl)quinolin-4(1H)-one

Target: IL Receptor, Caspase, Prostaglandin Receptor

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01174	DKK1 Protein, Rhesus, Recombinant (N256Q, His)	Rhesus	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-04811	DKK1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-00775	DKK1 Protein, Human, Recombinant (His)	Human	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-02287	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repa...
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-04346	PD-L2 Protein, Human, Recombinant (His)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293
	Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally ...
TMPY-00854	IL-1 alpha/IL-1A Protein, Human, Recombinant	Human	HEK293
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-01738	IL-1 alpha/IL-1A Protein, Mouse, Recombinant	Mouse	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-02118	IGFBP-6 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-bind...
TMPY-00978	Progranulin Protein, Human, Recombinant (His)	Human	HEK293
	Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPH-00009	OGT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc...
TMPY-02034	Siglec-2/CD22 Protein, Human, Recombinant (His)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-04083	Siglec-2/CD22 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05201	Siglec-2/CD22 Protein, Human, Recombinant	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-02420	HEMK2 Protein, Human, Recombinant (His)	Human	E. coli
	N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t...
TMPY-06151	Ara h 6 Protein, Arachis hypogaea, Recombinant (His)	Arachis hypogaea	Yeast
	Ara h 6 is a major peanut allergen showing similarity with Ara h 2 in many aspects. Ara h 6 is a major peanut allergen in children and adults. Ara h 6 has approximately the same seroprevalence as Ara h 2 and thus is con...
TMPY-04474	PFKFB3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of glycolysis. Highly phosphorylated PFKFB3 protein wa...
TMPY-04397	PAK-3 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are si...
TMPK-01353	IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-01354	IGF2R Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-01355	IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPY-02546	FUT8 Protein, Human, Recombinant (aa 68-575, His)	Human	Baculovirus-Insect Cells
	Alpha (1,6) fucosyltransferase 8, also known as FUT8, is a member of the glycosyltransferase family. Fucosyltransferases are the enzymes transferring fucose from GDP-Fuc to Gal in an alpha1,2-linkage and to GlcNAc in alp...
TMPK-01361	IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPY-03663	FUT8 Protein, Hamster, Recombinant (aa 68-575, His)	Hamster	Baculovirus-Insect Cells
	Alpha (1,6) fucosyltransferase 8, also known as FUT8, is a member of the glycosyltransferase family. Fucosyltransferases are the enzymes transferring fucose from GDP-Fuc to Gal in an alpha1,2-linkage and to GlcNAc in alp...
TMPY-05797	DKK1 Protein, Rat, Recombinant (His)	Rat	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-01175	DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)	Rhesus	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-05479	DKK1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPJ-00384	PFKM Protein, Human, Recombinant (His)	Human	Human Cells
	6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian ...
TMPH-02906	Sialidase-1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference ...
TMPY-01189	GFPT1 Protein, Human, Recombinant	Human	E. coli
	Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosami...
TMPH-00586	Beta-lactamase TEM Protein, E. coli, Recombinant (His)	E. coli	Yeast
	TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4...
TMPJ-00520	NANS Protein, Human, Recombinant (His)	Human	E. coli
	Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-de...
TMPH-00587	Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4...
TMPY-04749	MKK6 Protein, Human, Recombinant (S207D, T211D)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04364	MKK6 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04365	MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04748	MKK6 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPH-01080	Ceruloplasmin Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the ...
TMPK-01232	PLXNA1 Protein, Human, Recombinant (His)	Human	HEK293
	PLXNA1 (Plexin A1) is a member of plexin family that are the receptors of semaphorins. It is involved in cell migration and neuronal repulsion by affecting cytoskeletal remodeling. PLXNA1 can bind class 6 semaphorins and...
TMPY-03272	COL4A3 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix s...
TMPY-04479	PFKM Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-ty...
TMPH-02655	Ficolin 1/FCN1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of ...
TMPJ-00496	PGM2 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphoglucomutase-2 (PGM2) is a member of PGM family, which catalyzes the inter-conversion of sugar phosphates and participates in anabolic and catabolic reactions. When cells are grown in glucose, PGM catalyzes the con...
TMPH-01681	METTL4 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	N(6)-adenine-specific methyltransferase that can methylate both RNAs and DNA. Acts as a N(6)-adenine-specific RNA methyltransferase by catalyzing formation of N6,2'-O-dimethyladenosine (m6A(m)) on internal positions of U...
TMPK-01174	SLAMF6 Protein, Mouse, Recombinant (aa 31-239, His)	Mouse	HEK293
	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be wide...
TMPK-00651	SLAMF6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be wide...
TMPK-00222	SLAMF6 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be wide...
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DKK1 Protein, Rhesus, Recombinant (N256Q, His)

TMPY-01174

Species: Rhesus

Expression System: HEK293

DKK1 Protein, Mouse, Recombinant (His)

TMPY-04811

Species: Mouse

Expression System: HEK293

DKK1 Protein, Human, Recombinant (His)

TMPY-00775

Species: Human

Expression System: HEK293

Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)

TMPY-02287

Species: Human

Expression System: Baculovirus-Insect Cells

PD-L2 Protein, Human, Recombinant (His), Biotinylated

TMPY-04957

Species: Human

Expression System: HEK293

PD-L2 Protein, Human, Recombinant (His)

TMPY-04346

Species: Human

Expression System: HEK293

PD-L2 Protein, Human, Recombinant (mFc)

TMPY-05827

Species: Human

Expression System: HEK293

IL-1 alpha/IL-1A Protein, Human, Recombinant

TMPY-00854

Species: Human

Expression System: HEK293

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Mouse, Recombinant

TMPY-01738

Species: Mouse

Expression System: E. coli

IGFBP-6 Protein, Mouse, Recombinant (His)

TMPY-02118

Species: Mouse

Expression System: HEK293

Progranulin Protein, Human, Recombinant (His)

TMPY-00978

Species: Human

Expression System: HEK293

OGT Protein, Human, Recombinant (His & SUMO)

TMPH-00009

Species: Human

Expression System: E. coli

Siglec-2/CD22 Protein, Human, Recombinant (His)

TMPY-02034

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Mouse, Recombinant (His)

TMPY-04083

Species: Mouse

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)

TMPY-05566

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant

TMPY-05201

Species: Human

Expression System: HEK293

HEMK2 Protein, Human, Recombinant (His)

TMPY-02420

Species: Human

Expression System: E. coli

Ara h 6 Protein, Arachis hypogaea, Recombinant (His)

TMPY-06151

Species: Arachis hypogaea

Expression System: Yeast

PFKFB3 Protein, Human, Recombinant (His & GST)

TMPY-04474

Species: Human

Expression System: Baculovirus-Insect Cells

PAK-3 Protein, Human, Recombinant (His)

TMPY-04397

Species: Human

Expression System: Baculovirus-Insect Cells

IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)

TMPK-01353

Species: Human

Expression System: HEK293

IGF2R Protein, Human, Recombinant (His & Avi)

TMPK-01354

Species: Human

Expression System: HEK293

IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)

TMPK-01355

Species: Human

Expression System: HEK293

FUT8 Protein, Human, Recombinant (aa 68-575, His)

TMPY-02546

Species: Human

Expression System: Baculovirus-Insect Cells

IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01361

Species: Human

Expression System: HEK293

FUT8 Protein, Hamster, Recombinant (aa 68-575, His)

TMPY-03663

Species: Hamster

Expression System: Baculovirus-Insect Cells

DKK1 Protein, Rat, Recombinant (His)

TMPY-05797

Species: Rat

Expression System: HEK293

DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)

TMPY-01175

Species: Rhesus

Expression System: HEK293

DKK1 Protein, Human, Recombinant (hFc)

TMPY-05479

Species: Human

Expression System: HEK293

PFKM Protein, Human, Recombinant (His)

TMPJ-00384

Species: Human

Expression System: Human Cells

Sialidase-1 Protein, Mouse, Recombinant (His)

TMPH-02906

Species: Mouse

Expression System: E. coli

GFPT1 Protein, Human, Recombinant

TMPY-01189

Species: Human

Expression System: E. coli

Beta-lactamase TEM Protein, E. coli, Recombinant (His)

TMPH-00586

Species: E. coli

Expression System: Yeast

NANS Protein, Human, Recombinant (His)

TMPJ-00520

Species: Human

Expression System: E. coli

Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)

TMPH-00587

Species: E. coli

Expression System: E. coli

MKK6 Protein, Human, Recombinant (S207D, T211D)

TMPY-04749

Species: Human

Expression System: Baculovirus-Insect Cells

MKK6 Protein, Human, Recombinant (His & GST)

TMPY-04364

Species: Human

Expression System: Baculovirus-Insect Cells

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)

TMPY-04365

Species: Human

Expression System: Baculovirus-Insect Cells

MKK6 Protein, Human, Recombinant

TMPY-04748

Species: Human

Expression System: Baculovirus-Insect Cells

Ceruloplasmin Protein, Human, Recombinant (His & Myc)

TMPH-01080

Species: Human

Expression System: E. coli

PLXNA1 Protein, Human, Recombinant (His)

TMPK-01232

Species: Human

Expression System: HEK293

COL4A3 Protein, Rat, Recombinant (hFc)

TMPY-03272

Species: Rat

Expression System: HEK293

PFKM Protein, Human, Recombinant (His & GST)

TMPY-04479

Species: Human

Expression System: Baculovirus-Insect Cells

Ficolin 1/FCN1 Protein, Mouse, Recombinant (His)

TMPH-02655

Species: Mouse

Expression System: E. coli

PGM2 Protein, Human, Recombinant (His)

TMPJ-00496

Species: Human

Expression System: E. coli

METTL4 Protein, Human, Recombinant (His & Myc)

TMPH-01681

Species: Human

Expression System: E. coli

SLAMF6 Protein, Mouse, Recombinant (aa 31-239, His)

TMPK-01174

Species: Mouse

Expression System: HEK293

SLAMF6 Protein, Cynomolgus, Recombinant (His)

TMPK-00651

Species: Cynomolgus

Expression System: HEK293

SLAMF6 Protein, Human, Recombinant (His & Avi)

TMPK-00222

Species: Human

Expression System: HEK293

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Cat No.	Product Name
L2191	Anti-Breast Cancer Compound Library	1965 compounds
	A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

Libraries

Anti-Breast Cancer Compound Library

L2191

Compounds: 1965

NF-κB Signaling Compound Library

L3800

Compounds: 740

Chemokine Inhibitor Library

L7600

Compounds: 59