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BRCA1-IN-2

Catalog No. T10601   CAS 1622262-55-8

BRCA1-IN-2 is a cell membrane-crossing BRCA1 protein-protein interaction (PPI) inhibitor with antitumor activity that acts by disrupting the interaction of BRCA1 (BRCT)2 with proteins.

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BRCA1-IN-2 Chemical Structure
BRCA1-IN-2, CAS 1622262-55-8
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Purity: 98.04%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description BRCA1-IN-2 is a cell membrane-crossing BRCA1 protein-protein interaction (PPI) inhibitor with antitumor activity that acts by disrupting the interaction of BRCA1 (BRCT)2 with proteins.
Targets&IC50 BRCA1:0.31 μM, BRCA1:0.3 μM (Kd)
Molecular Weight 544.54
Formula C26H33N4O7P
CAS No. 1622262-55-8

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL(146.91 mM), Sonification is recommeded.

TargetMolReferences and Literature

1. Na Z, et al. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods Mol Biol. 2017;1518:139-156.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BRCA1-IN-2 1622262-55-8 Others BRCA-1-IN-2 BRCA1 IN 2 BRCA1IN2 inhibitor inhibit

 

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