Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | 8-10 weeks | $ 729.00 | |
100 mg | 8-10 weeks | $ 1,310.00 |
Description | BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator with antifibrotic effect. It increases the activity of sGC in a nitric oxide-independent manner. |
In vivo | BAY 60-2770 (0.1-0.3 mg/kg; p.o.) attenuates liver fibrosis in two rat models [1]. BAY 60-2770 (1 mg/kg; p.o.; daily from the 10th to the 12th week) results in amelioration of bladder dysfunction in high-fat obese mice [2]. |
Molecular Weight | 623.63 |
Formula | C35H33F4NO5 |
CAS No. | 1027642-43-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BAY 60-2770 1027642-43-8 Others BAY 60 2770 BAY 602770 inhibitor inhibit