Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent.
Pack Size | Availability | Price/USD | Quantity |
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25 mg | 10-14 weeks | Inquiry | |
50 mg | 10-14 weeks | Inquiry | |
100 mg | 10-14 weeks | Inquiry |
Description | Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent. |
In vitro | Aniline-MPB-amino-C3-PBD (compound 16) shows cytotoxicity with IC50s of 77, 72, 79, 184.3, 61.5, and 145.6 nM for SW48, LIM1215, SW620, U138-MG, A431, and REH cells, respectively. It effectively stabilizes DNA with a degree of sequence-specificity. Aniline-MPB-amino-C3-PBD possesses potent antibacterial effects against the gram-negative strain E. coli K12 with the potency of 2 pg/mL determined. |
Molecular Weight | 758.86 |
Formula | C42H46N8O6 |
CAS No. | 2412923-79-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aniline-MPB-amino-C3-PBD 2412923-79-4 Others AnilineMPBaminoC3PBD Aniline MPB amino C3 PBD Aniline-MPB-amino-C-3-PBD inhibitor inhibit