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Home > Membrane transporter/Ion channel > TRP/TRPV Channel > AMG-517

AMG-517

Catalog No. T6379    CAS 659730-32-2    Synonyms: AMG 517

AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.

Pack Size Availability Price/USD Quantity
2 mg In Stock 71.00
5 mg In Stock 128.00
10 mg In Stock 173.00
25 mg In Stock 364.00
50 mg In Stock 645.00
1 mL * 10 mM (in DMSO) In Stock 137.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.

Receptor:

TRPV1;

Chemical Information:
Molecular Weight 430.40
Formula C20H13F3N4O2S
CAS Number 659730-32-2
Solubility

DMSO: 43 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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