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3-Hydroxyphloretin
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Catalog No. TN13995 Copy Product Info
Purity: 99.49%
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3-Hydroxyphloretin is a natural dihydrochalcone compound mainly found in plants such as Malus doumeri var. formosana. 3-Hydroxyphloretin inhibits tyrosinase, thereby reducing melanin production, showing potential application prospects in skin whitening and pigmentation-related research. In addition, 3-Hydroxyphloretin also possesses certain antibacterial activity and can be used for screening and development of antibacterial functional molecules.
Cas No. 57765-66-9
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $691 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.49%
Appearance:Solid
Color:Yellow
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 3-Hydroxyphloretin is a natural dihydrochalcone compound mainly found in plants such as Malus doumeri var. formosana. 3-Hydroxyphloretin inhibits tyrosinase, thereby reducing melanin production, showing potential application prospects in skin whitening and pigmentation-related research. In addition, 3-Hydroxyphloretin also possesses certain antibacterial activity and can be used for screening and development of antibacterial functional molecules. |
| In vitro | Method: 3-Hydroxyphloretin was produced by hydrolysis of purified 3-hydroxyphlorizin, structurally identified by LC-ESI-MS and NMR, and tested in DPPH and ABTS radical-scavenging assays and MTT assays using five cancer cell lines.
Result: 3-Hydroxyphloretin showed the strongest antioxidant activity among the seven tested dihydrochalcones, whereas its cancer-cell cytotoxicity was weaker than that of sieboldin and 3-hydroxyphlorizin.[1] |
| Molecular Weight | 290.27 |
| Formula | C15H14O6 |
| Cas No. | 57765-66-9 |
| Smiles | O=C(C=1C(O)=CC(O)=CC1O)CCC2=CC=C(O)C(O)=C2 |
| Relative Density. | no data available |
| Storage | Keep away from moisture,Keep away from direct sunlight,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Product Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: 3-Hydroxyphloretin chemical structure | 3-Hydroxyphloretin in vitro | 3-Hydroxyphloretin formula | 3-Hydroxyphloretin molecular weight
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