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Apoptosis Apoptosis 2-Methoxynaphthoquinone

2-Methoxynaphthoquinone

Catalog No. T3008   CAS 2348-82-5
Synonyms: 2-Methoxy-1,4-naphthoquinone, 2-Methoxy-p-naphthoquinone

MNQ induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these signaling pathways were stimulated by oxidative DNA damage caused by increased ROS generation in MNQ-treated A549 cells.

2-Methoxynaphthoquinone, CAS 2348-82-5
Pack Size Availability Price/USD Quantity
25 mg In stock 38.00
50 mg In stock 50.00
100 mg In stock 73.00
200 mg In stock 132.00
1 mL * 10 mM (in DMSO) In stock 50.00
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Purity 99.41%
Biological Description
Chemical Properties
Storage & Solubility Information
Description MNQ induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these signaling pathways were stimulated by oxidative DNA damage caused by increased ROS generation in MNQ-treated A549 cells.
Targets&IC50 JNK ,   p38 MAPK
Synonyms 2-Methoxy-1,4-naphthoquinone , 2-Methoxy-p-naphthoquinone
Purity 99.41%
Molecular Weight 188.18
Formula C11H8O3
CAS No. 2348-82-5

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
2. Parat V, Onteniente B, Maruotti J. A high‐throughput screening platform for pigment regulating agents using pluripotent stem cell‐derived melanocytes[J]. Experimental Dermatology. 2020 3. Parat V, Onteniente B, Maruotti J. A high-throughput screening platform for pigment regulating agents using pluripotent stem cell derived melanocytes[J]. Experimental Dermatology. 2020.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Natural Compound Library for HTS Anti-cancer Compound Library Stem cell Differentiation Compound Library Anti-infection Compound Library Apoptosis Compound Library Oxidation-Reduction Compound Library Selected Plant-sourced Compound Library Kinase Inhibitor Library GPCR Compound Library TGF-beta/Smad Compound Library Neural Regeneration Compound Library Osteogenesis-related Compound Library Anti-aging Compound Library Antitumor Natural Products Library Traditional Chinese Medicine Monomer Library

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