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GPCR/G Protein Neurokinin Receptor [Lys5,MeLeu9,Nle10]-NKA(4-10)

[Lys5,MeLeu9,Nle10]-NKA(4-10)

Catalog No. TP1883   CAS 137565-28-7
Purity 100.00%

Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).

[Lys5,MeLeu9,Nle10]-NKA(4-10)
CAS 137565-28-7
Pack Size Availability Price/USD Quantity
1 mg In stock 193.00
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Purity 98.00%
Purity 100.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
Targets&IC50 NK2,  
Synonyms
Purity 100.00%
Appearance solid
Molecular Weight 804.00
Formula C39H65N9O9
CAS No. 137565-28-7

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

water: 1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Chassaing et al (1991) Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 19 91 PMID: 2. Matuszek et al (1998) An investigation of tachykinin NK2 receptor subtypes in the rat. Eur.J.Pharmacol. 352 103 PMID: 3. Burcher et al (2008) Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomet. and in diverticular disease and ulcerative colitis. J.Pharmacol.Exp.Ther. 324 170 PMID:

Related Products

Related compounds with same targets
Neurokinin A GR-73632 [Lys5,MeLeu9,Nle10]-NKA(4-10)

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