Compound Libraries Cell cycle related Compound Library

Cell cycle related Compound Library

Catalog No. L8100
  Library Compound List   Excel SDF

Cell cycle, the ordered sequence of events that occur in a cell in preparation for cell division, is also divided into two periods: interphase and the mitotic (M) phase. Interphase itself is split into different phases: G1 phase, S phase and G2 phase. Cell Cycle related compounds rely on differing mechanisms of action to regulate the normal progression of the cell cycle. Some of these compounds interfere with CDK/cyclin complexes leaving cells stuck at the G2/M phase border, while others affect CaMKII phosphorylation, inducing arrest at the G1 phase. Other mechanisms of action include interference with RNA function and inhibition of protein synthesis. Many of these compounds ultimately induce apoptosis as a result of their interruption of the cell cycle. This library can be used for anti-cancer drug screening.

The TargetMol’s Cell Cycle Compound Library, a unique collection of 228 cell cycle related compounds, can be used for research in cell cycle and related drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 3420.00
250 μL * 10 mM (in DMSO) 5928.00
1 mg 5928.00
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Product Description

  • A unique collection of 228 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.;
  • Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L8100)

Library Composition

CDK (56)
Aurora Kinase (20)
ROCK (15)
Chk (11)
GSK-3 (10)
PLK (10)
Src (9)
JAK (9)
PKA (8)
Rho (6)
FLT (6)
FGFR (5)
PKC (5)
c-Myc (4)
c-RET (4)
cell cycle arrest (4)
Casein Kinase (4)
Bcr-Abl (3)
cholecystokinin (3)
ERK (3)
Trk receptor (3)
Tyrosine Kinases (3)
PDK (3)
Serine/threonin kinase (3)
SGK (2)
PD-1/PD-L1 (2)
S6 Kinase (2)
p38 MAPK (2)
PYK2 (2)
Raf (2)
FAK (2)
Ferroptosis (2)
KSP (2)
MEK (2)
c-Kit (2)
DYRK (2)
Akt (2)
Apoptosis inducer (1)
CCR (1)
c-Fms (1)
EGFR (1)
Epigenetic Reader Domain (1)
CXCR (1)
c-Met/HGFR (1)
mTOR (1)
LIM Kinase (1)
LRRK2 (1)
JNK (1)
IκB/IKK (1)
Adenosine Receptor (1)
Glucokinase (1)
GPR (1)
GRK (1)
P450 (1)
Pim (1)
Serine Protease (1)
TAM Receptor (1)
Topoisomerase (1)
Wee1 (1)