Serotoninor5-hydroxytryptamine(5-HT) is amonoamine neurotransmitter, derivative from the amino acidtryptophan, and mainly located in the enterochromaffin cells in the GI tract and central nervous system (CNS). It has a popular image as a contributor to feelings of well-being andhappiness, though its actual biological function is complex and multifaceted, modulating cognition, reward, learning, memory, and numerous physiological processes. Serotonin receptors, are a group ofG protein-coupled receptorandligand-gated ion channelsfound in thecentralandperipheral nervous systems. They can be divided into 7 families ofG protein-coupled receptorsexcept for the5-HT3receptor, aligand-gated ion channel, which activate anintracellularsecond messengercascade to produce an excitatory or inhibitory response. They mediate bothexcitatory and inhibitoryneurotransmission, influencing various biological and neurological processes. The serotonin receptors are the target of a variety of pharmaceutical and recreational drugs, including manyantidepressants,antipsychotics,anorectics,antiemetics,gastroprokinetic agents,antimigraine agents,hallucinogens, andentactogens.
The Serotonin (5-HT) Compound Library by TargetMol, collecting 134 small chemicals targeting serotonin receptors, can be used for high throughput screening and high content screening, and drug discovery in neurological disorders.
|100 μL * 10 mM (in DMSO)||USD 2158.00|
|250 μL * 10 mM (in DMSO)||USD 3600.00|
|1 mg||USD 3600.00|
The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.