Scientists already found that the isomers or metabolites of many existing drugs show biological activity. For example, Levopropoxyphene is an antitussive, approved by FDA, but its enantiomer, Dextropropoxyphene, has an analgesic effect; L-sotalol is alpha-blocker while d-sotalol is antiarrythmic. Currently, knowledge of isomerism has helped us in introducing safer and more effective drug alternatives of the newer as well as existing drugs. These compounds that have rich pharmacological evaluation data are ideal as entry point for drug repurposing.
The TargetMol’s Selected drug metabolites/isomers Library, a unique collection of 200 drug isomers/metabolites with a great diversity, can be used for drug screening.
|100 μL * 10 mM (in DMSO)||2280.00|
|250 μL * 10 mM (in DMSO)||3890.00|