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Compound Libraries Protease Inhibitor Library

Protease Inhibitor Library

Catalog No. L1100
  Library Compound List   Excel SDF

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of the proteasome, such as bortezomib are now front-line drugs for the treatment of multiple myeloma. Marimastat and batimastat are two of the matrix metalloproteinase inhibitors that can be used to treat cancer.

The Protease Inhibitor Library by TargetMol, containing 295 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 6430.00
250 μL * 10 mM (in DMSO) 10606.00
1 mg 10606.00
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Product Description

  • A unique collection of 295 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
  • Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice.
Request Library Compound List (L1100)

Library Composition

HIV Protease (27)
MMP (18)
Serine Protease (16)
Proteasome (15)
Caspase (14)
Cysteine Protease (13)
Gamma-secretase (12)
HCV Protease (11)
DPP-4 (11)
Beta Amyloid (6)
PPAR (4)
DUB (3)
COX (3)
Microtubule Associated (2)
NF-κB (2)
p97 (2)
HIF (2)
DNA/RNA Synthesis (2)
BACE (2)
Akt (2)
RAAS (2)
ribosome (1)
S1P Receptor (1)
p38 MAPK (1)
P450 (1)
Sodium Channel (1)
Somatostatin (1)
Telomerase (1)
Thrombin (1)
TNF (1)
Topoisomerase (1)
Transferase (1)
UGT (1)
ALK (1)
Aminopeptidase (1)
Antifection (1)
ASK (1)
Aurora Kinase (1)
Bcr-Abl (1)
Carboxypeptidase(CPG2) (1)
CDK (1)
CFTR (1)
ERK (1)
Estrogen/progestogen Receptor (1)
Free radical scavengers (1)
HIF/HIF Prolyl-Hydroxylase (1)
Histamine Receptor (1)
HSV (1)
IGF-1R (1)
IκB/IKK (1)
JNK (1)
Lipoxygenase (1)
LTR (1)
PAI-1 (1)
P-gp (1)
Potassium Channel (1)